About   Help   FAQ
Ifngr2
Gene Detail
 Symbol
Name
ID
Ifngr2
interferon gamma receptor 2
MGI:107654
Synonyms Ifgr2, Ifgt
Feature Type protein coding gene
Genetic Map
Chromosome 16
53.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr16:91547072-91565169 bp, + strand
From VEGA annotation of GRCm38

  18098 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4041  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog; 1 chicken

Protein SuperFamily: interleukin-10 receptor beta chain
Gene Tree: Ifngr2

Human
homologs
Human Homolog IFNGR2, interferon gamma receptor 2 (interferon gamma transducer 1)
NCBI Gene ID 3460
neXtProt AC  NX_P38484
Human Synonyms  AF-1, IFGR2, IFNGT1
Human Chr (Location)  21q22.11; chr21:33402896-33437521 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human IFNGR2
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Genomic Mutations involving Ifngr2 (3)
 
Mice homozygous for disruptions in this gene develop normally.
 
Human Diseases Modeled Using Mouse Ifngr2 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Ifngr2 interacts with 199 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Component endoplasmic reticulum, plasma membrane
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (244)    Tissues (157)    Images (39)
Theiler Stages: 13, 15, 17, 20, 22, 23, 26, 27, 28
Assay TypeResults
RNA in situ 226
RT-PCR 18
cDNA source data(55)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(60) Genomic(1) cDNA(56) Primer pair(3)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000028337 (Evidence)
Ensembl Gene ModelENSMUSG00000022965 (Evidence)
Entrez Gene15980 (Evidence)
UniGene249364
DFCITC1577984
DoTSDT.530377
NIA Mouse Gene IndexU043545
Consensus CDS ProjectCCDS28327.1
International Mouse Knockout Project StatusIfngr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028337 VEGA Gene Model | MGI Sequence Detail 18098 C57BL/6J ±  kb
transcript OTTMUST00000070230 VEGA | MGI Sequence Detail 3254 Not Applicable 
polypeptide OTTMUSP00000035758 VEGA | MGI Sequence Detail 332 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(2) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR015373 Interferon alpha/beta receptor, beta chain
Protein Ontology PR:000008926 interferon-gamma receptor beta chain
References (Earliest) J:11127 Hibino Y, et al., Expression and reconstitution of a biologically active mouse interferon gamma receptor in hamster cells. Chromosomal location of an accessory factor. J Biol Chem. 1991 Apr 15;266(11):6948-51
(Latest) J:190356 Schurgers E, et al., Pulmonary inflammation in mice with collagen-induced arthritis is conditioned by complete Freund's adjuvant and regulated by endogenous IFN-gamma. Eur J Immunol. 2012 Dec;42(12):3223-34
All references(61)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-11216, MGD-MRK-25614, MGD-MRK-36229

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory