Embryos homozygous for a targeted null mutation die prior to E7.5. In culture, mutant blastocysts are viable up to 2 days but show subsequent apoptosis of the inner cell mass. Mutant cells exhibit major chromosome condensation and segregation defects as well as gross defects in nuclear organization.
|VEGA Gene Model||OTTMUSG00000037656 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000015120 (Evidence)|
|Entrez Gene||22196 (Evidence)|
|DFCI||TC1733251, TC1573910, TC1580316, TC1630812, TC1613530, TC1599272|
|DoTS||DT.537369, DT.528079, DT.110578340, DT.97388528, DT.110578317, DT.101405478, DT.91360096, DT.101405474, DT.103575320, DT.101405491, DT.99868625|
|PDB||1U9A, 1U9B, 2VRR, 2UYZ|
|Consensus CDS Project||CCDS28513.1|
|International Mouse Knockout Project Status||Ube2i|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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