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Gfm1
Gene Detail
 Symbol
Name
ID
Gfm1
G elongation factor, mitochondrial 1
MGI:107339
Synonyms D3Wsu133e
Feature Type protein coding gene
Genetic Map
Chromosome 3
30.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:67430096-67476529 bp, + strand
From VEGA annotation of GRCm38

  46434 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6449  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: translation elongation factor G
Gene Tree: Gfm1

Human
homologs
Human Homolog GFM1, G elongation factor, mitochondrial 1
NCBI Gene ID 85476
neXtProt AC  NX_Q96RP9
Human Synonyms  COXPD1, EFG, EFG1, EFGM, EGF1, GFM, hEFG1
Human Chr (Location)  3q25; chr3:158644497-158692572 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human GFM1
Alleles
and
phenotypes
All alleles(4) : Gene trapped(3) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process GTP catabolic process, mitochondrial translational elongation, ...
Component intracellular, mitochondrion
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (6)    Tissues (2)   
Theiler Stages: 11
Assay TypeResults
RT-PCR 6
cDNA source data(117)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(119) cDNA(118) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000029074 (Evidence)
Ensembl Gene ModelENSMUSG00000027774 (Evidence)
Entrez Gene28030 (Evidence)
UniGene122466
DFCITC1574367, TC1602330
DoTSDT.101725996, DT.534867, DT.97333817
NIA Mouse Gene IndexU003306
Consensus CDS ProjectCCDS38449.1
International Mouse Knockout Project StatusGfm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029074 VEGA Gene Model | MGI Sequence Detail 46434 C57BL/6J ±  kb
transcript OTTMUST00000072125 VEGA | MGI Sequence Detail 4078 Not Applicable 
polypeptide OTTMUSP00000037052 VEGA | MGI Sequence Detail 751 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(387 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009022 Elongation factor G, III-V domain
InterPro IPR000795 Elongation factor, GTP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR020568 Ribosomal protein S5 domain 2-type fold
InterPro IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
InterPro IPR005225 Small GTP-binding protein domain
InterPro IPR004540 Translation elongation factor EFG/EF2
InterPro IPR005517 Translation elongation factor EFG/EF2, domain IV
InterPro IPR000640 Translation elongation factor EFG, V domain
InterPro IPR004161 Translation elongation factor EFTu/EF1A, domain 2
InterPro IPR009000 Translation elongation/initiation factor/Ribosomal, beta-barrel
Protein Ontology PR:000007943 elongation factor G, mitochondrial
References (Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGD-MRK-35805, MGI:2139995

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory