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Fyco1
Gene Detail
Symbol

Name
ID
Fyco1
FYVE and coiled-coil domain containing 1
MGI:107277
Synonyms
2810409M01Rik, Mem2, ZFYVE7
Feature Type
protein coding gene
Genetic Map
Chromosome 9
74.52 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr9:123789886-123851886 bp, - strand
From VEGA annotation of GRCm38

  62001 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11561  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: FYCO1
Gene Tree: Fyco1

Human
homologs
FYCO1, FYVE and coiled-coil domain containing 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 79443
neXtProt AC: NX_Q9BQS8

Human Synonyms: CATC2, CTRCT18, RUFY3, ZFYVE7

Human Chr (Location): 3p21.31; chr3:45917899-45995824 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human FYCO1

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Fyco1 interacts with 357 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process plus-end-directed vesicle transport along microtubule, transport
Component autophagosome, cytoplasmic vesicle, ...
Function metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (42)    Tissues (28)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 38
RT-PCR 4
cDNA source data(67)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(70) cDNA(69) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000044623 (Evidence)
Ensembl Gene Model ENSMUSG00000025241 (Evidence)
Entrez Gene 17281 (Evidence)
UniGene 252941
DFCI TC1624764, TC1585441, TC1655583
DoTS DT.103559949, DT.488945, DT.99852426, DT.55259151
NIA Mouse Gene Index U031481
Consensus CDS Project CCDS40819.1
International Mouse Phenotyping Consortium Status Fyco1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044623 VEGA Gene Model | MGI Sequence Detail 62001 C57BL/6J ±  kb
transcript OTTMUST00000117392 VEGA | MGI Sequence Detail 7468 Not Applicable 
polypeptide OTTMUSP00000065657 VEGA | MGI Sequence Detail 1437 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(4) UniProt(1)
Polymorphisms
PCR(1) : SNPs within 2kb(1140 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009038 GOLD
InterPro IPR004012 RUN
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR017455 Zinc finger, FYVE-related
InterPro IPR000306 Zinc finger, FYVE-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000029502 FYVE and coiled-coil domain-containing protein 1
References
(Earliest) J:40042 Heyer BS, et al., New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo. Mol Reprod Dev. 1997 Jun;47(2):148-56
(Latest) J:209359 Ma J, et al., Cutting edge: FYCO1 recruitment to dectin-1 phagosomes is accelerated by light chain 3 protein and regulates phagosome maturation and reactive oxygen production. J Immunol. 2014 Feb 15;192(4):1356-60
All references(39)
Other
accession IDs
MGD-MRK-35742, MGI:1917454

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory