Fyco1
Gene Detail

Symbol Name ID

Fyco1 FYVE and coiled-coil domain containing 1 MGI:107277

Synonyms

2810409M01Rik, Mem2, ZFYVE7

Feature Type

protein coding gene

Genetic Map

Chromosome 9

74.52 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(8)

Sequence Map

Chr9:123789510-123851899 bp, - strand From NCBI annotation of GRCm38   62390 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:11561  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fyco1

Human homologs

Human Homolog		FYCO1, FYVE and coiled-coil domain containing 1
NCBI Gene ID		79443
neXtProt AC		NX_Q9BQS8
Human Synonyms		CATC2, CTRCT18, RUFY3, ZFYVE7
Human Chr (Location)		3p21.31; chr3:45959391-46037316 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human FYCO1

Alleles and phenotypes

All alleles(2) : Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	plus-end-directed vesicle transport along microtubule, transport
Component	autophagic vacuole, cytoplasmic vesicle, ...
Function	metal ion binding

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (45)    Tissues (31)    Images (12)
Theiler Stages: 1, 2, 3, 4, 23, 28

Assay Type	Results
RNA in situ	38
RT-PCR	7

cDNA source data(67)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(70) cDNA(69) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000025241 (Evidence)
Entrez Gene	17281 (Evidence)
UniGene	252941
DFCI	TC1585441, TC1624764, TC1655583
DoTS	DT.103559949, DT.488945, DT.55259151, DT.99852426
NIA Mouse Gene Index	U031481
Consensus CDS Project	CCDS40819.1
International Mouse Knockout Project Status	Fyco1

Sequences

Length	Strain/Species
genomic	17281	NCBI Gene Model | MGI Sequence Detail	62390	C57BL/6J
transcript	NM_148925	RefSeq | MGI Sequence Detail	7949	C57BL/6
polypeptide	Q8VDC1	UniProt | EBI | MGI Sequence Detail	1437	Not Applicable

All sequences(34) RefSeq(4) UniProt(1)

Polymorphisms

PCR(1) : SNPs within 2kb(1143 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR009038	GOLD
InterPro	IPR004012	RUN
InterPro	IPR011011	Zinc finger, FYVE/PHD-type
InterPro	IPR017455	Zinc finger, FYVE-related
InterPro	IPR000306	Zinc finger, FYVE-type
InterPro	IPR013083	Zinc finger, RING/FYVE/PHD-type
Protein Ontology	PR:000029502	FYVE and coiled-coil domain-containing protein 1

Graphical View of Protein Domain Structure

References

(Earliest) J:40042 Heyer BS, et al., New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo. Mol Reprod Dev. 1997 Jun;47(2):148-56
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(38)

Other accession IDs

MGD-MRK-35742, MGI:1917454