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Fyco1 Gene Detail
Summary
  • Symbol
    Fyco1
  • Name
    FYVE and coiled-coil domain containing 1
  • Synonyms
    2810409M01Rik, Mem2, ZFYVE7
  • Feature Type
    protein coding gene
  • IDs
    MGI:107277
    NCBI Gene: 17281
Location & Maps
more
  • Sequence Map
    Chr9:123789886-123851886 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      62001 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 74.52 cM, cytoband F
  • Mapping Data
    8 experiments
Homology
more
  • Human Ortholog
    FYCO1, FYVE and coiled-coil domain containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FYCO1, FYVE and coiled-coil domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CATC2, CTRCT18, RUFY3, ZFYVE7
  • Links
    NCBI Gene ID: 79443
    neXtProt AC: NX_Q9BQS8

  • Chr Location
    3p21.31; chr3:45917899-45995824 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human FYCO1 associations

Human Disease Mouse Models
       Cataract 18; CTRCT18   OMIM: 610019
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044623 VEGA Gene Model | MGI Sequence Detail 62001 C57BL/6J ±  kb
transcript OTTMUST00000117392 VEGA | MGI Sequence Detail 7468 Not Applicable  
polypeptide OTTMUSP00000065657 VEGA | MGI Sequence Detail 1437 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1136 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    cDNA 69
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35742, MGI:1917454
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:40042 Heyer BS, et al., New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo. Mol Reprod Dev. 1997 Jun;47(2):148-56
  • Latest
    J:209359 Ma J, et al., Cutting edge: FYCO1 recruitment to dectin-1 phagosomes is accelerated by light chain 3 protein and regulates phagosome maturation and reactive oxygen production. J Immunol. 2014 Feb 15;192(4):1356-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory