Fyco1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fyco1
FYVE and coiled-coil domain containing 1
MGI:107277

10 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fyco1^em1(IMPC)J/Fyco1^em1(IMPC)J C57BL/6NJ-Fyco1^em1(IMPC)J/Mmjax	cataract	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
Fyco1^tm1.1Arte/Fyco1^tm1.1Arte Tg(Prm-cre)58Og/0 involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J * C57BL/6NTac	abnormal endoplasmic reticulum morphology	J:336796
	abnormal Golgi apparatus morphology	J:336796
	abnormal lens epithelium morphology	J:336796
	abnormal lens fiber morphology	J:336796
	abnormal phospholipid level	J:336796
	cataract	J:336796
	impaired autophagy	J:336796
	mature cataract	J:336796
Fyco1^tm1.2Arte/Fyco1^tm1.2Arte involves: C57BL/6J * C57BL/6N * C57BL/6NTac * FVB/N	abnormal endoplasmic reticulum morphology	J:336796
	abnormal Golgi apparatus morphology	J:336796
	abnormal lens epithelium morphology	J:336796
	abnormal lens fiber morphology	J:336796
	abnormal phospholipid level	J:336796
	cataract	J:336796
	impaired autophagy	J:336796
	mature cataract	J:336796

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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