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Coq7
Gene Detail
Symbol

Name
ID
Coq7
demethyl-Q 7
MGI:107207
Synonyms
clk-1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
63.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:118509659-118533356 bp, - strand
From VEGA annotation of GRCm38

  23698 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6953  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: COQ7
Gene Tree: Coq7

Human
homologs
COQ7, coenzyme Q7 homolog, ubiquinone (yeast)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10229
neXtProt AC: NX_Q99807

Human Synonyms: CAT5, CLK1, CLK-1

Human Chr (Location): 16p12.3; chr16:19067595-19080095 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(8) Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for null mutations in this gene are embryonic lethal during mid-gestation with aborted neurogenesis and abnormal mitochondria.
 
Phenotype Images(1)
Interactions
Coq7 interacts with 21 markers (Mir7-1, Mir128-1, Mir128-2, ...)
Expression
Literature Summary: (6 records)
Data Summary: Results (123)    Tissues (105)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
Northern blot 16
Western blot 12
cDNA source data(36)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase coq7 ; ZFIN coq7    NEW 
Molecular
reagents
All nucleic(38) cDNA(38)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000025111 (Evidence)
Ensembl Gene Model ENSMUSG00000030652 (Evidence)
Entrez Gene 12850 (Evidence)
UniGene 20634
DFCI TC1576973
DoTS DT.101388773, DT.521959
NIA Mouse Gene Index U029172
EC 1.14.13.-
Consensus CDS Project CCDS21771.1
International Mouse Phenotyping Consortium Status Coq7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025111 VEGA Gene Model | MGI Sequence Detail 23698 C57BL/6J ±  kb
transcript OTTMUST00000061776 VEGA | MGI Sequence Detail 1215 Not Applicable 
polypeptide OTTMUSP00000030375 VEGA | MGI Sequence Detail 337 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(4) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(363 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009078 Ferritin-like superfamily
InterPro IPR012347 Ferritin-related
InterPro IPR011566 Ubiquinone biosynthesis protein Coq7
Protein Ontology PR:000005756 ubiquinone biosynthesis protein COQ7
References
(Earliest) J:33381 Jonassen T, et al., Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. (Correction appears in Arch Biochem Biophys 1996; 335(1):227). Arch Biochem Biophys. 1996 Jun 15;330(2):285-9
(Latest) J:221897 Wang Y, et al., Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis. Nat Commun. 2015;6:6393
All references(49)
Other
accession IDs
MGD-MRK-35669

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory