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Coq7
Gene Detail
 Symbol
Name
ID
Coq7
demethyl-Q 7
MGI:107207
Synonyms clk-1
Feature Type protein coding gene
Genetic Map
Chromosome 7
63.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:118509659-118533356 bp, - strand
From VEGA annotation of GRCm38

  23698 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6953  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Coq7

Human
homologs
Human Homolog COQ7, coenzyme Q7 homolog, ubiquinone (yeast)
NCBI Gene ID 10229
neXtProt AC  NX_Q99807
Human Synonyms  CAT5, CLK1, CLK-1
Human Chr (Location)  16p12.3; chr16:19067595-19080095 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(8) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for null mutations in this gene are embryonic lethal during mid-gestation with aborted neurogenesis and abnormal mitochondria.
 
Phenotype Images(1)
Interactions
Coq7 interacts with 21 markers (Mir7-1, Mir128-1, Mir128-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process age-dependent response to oxidative stress, cellular response to oxidative stress, ...
Component membrane, mitochondrial inner membrane, ...
Function metal ion binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (123)    Tissues (104)    Images (10)
Theiler Stages: 15, 19, 22, 28
Assay TypeResults
RNA in situ 95
Northern blot 16
Western blot 12
cDNA source data(36)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(38) cDNA(38)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000025111 (Evidence)
Ensembl Gene ModelENSMUSG00000030652 (Evidence)
Entrez Gene12850 (Evidence)
UniGene20634
DFCITC1576973
DoTSDT.101388773, DT.521959
NIA Mouse Gene IndexU029172
Consensus CDS ProjectCCDS21771.1
International Mouse Knockout Project StatusCoq7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025111 VEGA Gene Model | MGI Sequence Detail 23698 C57BL/6J ±  kb
transcript OTTMUST00000061776 VEGA | MGI Sequence Detail 1215 Not Applicable 
polypeptide OTTMUSP00000030375 VEGA | MGI Sequence Detail 337 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(6) UniProt(3)
Polymorphisms RFLP(1) : SNPs within 2kb(363 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009078 Ferritin-like superfamily
InterPro IPR012347 Ferritin-related
InterPro IPR011566 Ubiquinone biosynthesis protein Coq7
Protein Ontology PR:000005756 ubiquinone biosynthesis protein COQ7
References (Earliest) J:33381 Jonassen T, et al., Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. (Correction appears in Arch Biochem Biophys 1996; 335(1):227). Arch Biochem Biophys. 1996 Jun 15;330(2):285-9
(Latest) J:202240 Wang Y, et al., Mitochondrial respiration without ubiquinone biosynthesis. Hum Mol Genet. 2013 Dec 1;22(23):4768-83
All references(47)
Other
accession IDs
MGD-MRK-35669

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory