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Gpld1 Gene Detail
Summary
  • Symbol
    Gpld1
  • Name
    glycosylphosphatidylinositol specific phospholipase D1
  • Synonyms
    6330541J12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:106604
    NCBI Gene: 14756
  • Gene Overview
    MyGene.info: GPLD1
Location & Maps
more
  • Sequence Map
    Chr13:24943152-24990753 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      47602 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 10.79 cM
  • Mapping Data
    7 experiments
Homology
more
  • Human Ortholog
    GPLD1, glycosylphosphatidylinositol specific phospholipase D1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GPLD1, glycosylphosphatidylinositol specific phospholipase D1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GPIPLD, GPIPLDM, PIGPLD, PIGPLD1, PLD
  • Links
    NCBI Gene ID: 2822
    neXtProt AC: NX_P80108

  • Chr Location
    6p22.1; chr6:24425832-24495043 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Gpld1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000734 VEGA Gene Model | MGI Sequence Detail 47602 C57BL/6J ±  kb
transcript OTTMUST00000001378 VEGA | MGI Sequence Detail 3476 Not Applicable  
polypeptide OTTMUSP00000000654 VEGA | MGI Sequence Detail 842 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    469 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-35061, MGI:1924474, MGI:2145449
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 11
    Phenotypes 12
  • Earliest
    J:190011 Metz CN, et al., Production of the glycosylphosphatidylinositol-specific phospholipase D by the islets of Langerhans. J Biol Chem. 1991 Sep 25;266(27):17733-6
  • Latest
    J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory