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Spg21
Gene Detail
 Symbol
Name
ID
Spg21
spastic paraplegia 21 homolog (human)
MGI:106403
Synonyms ACP33, BM-019, D9Wsu18e, GL010
Feature Type protein coding gene
Genetic Map
Chromosome 9
35.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr9:65460937-65488470 bp, + strand
From NCBI annotation of GRCm38

  27534 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9603  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Spg21

Human
homologs
Human Homolog SPG21, spastic paraplegia 21 (autosomal recessive, Mast syndrome)
NCBI Gene ID 51324
neXtProt AC  NX_Q9NZD8
Human Synonyms  ACP33, GL010, MAST
Human Chr (Location)  15q21-q22; chr15:64963021-64989946 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SPG21
Alleles
and
phenotypes
All alleles(11) : Targeted(2) Gene trapped(9)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process biological_process
Component cytoplasm, cytosol, ...
Function CD4 receptor binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (46)    Tissues (5)    Images (19)
Theiler Stages: 11, 23
Assay TypeResults
RNA in situ 40
RT-PCR 6
cDNA source data(84)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(86) cDNA(85) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000032388 (Evidence)
Entrez Gene27965 (Evidence)
UniGene272475
DFCITC1572743
DoTSDT.535362, DT.94263986, DT.97357082
NIA Mouse Gene IndexU010637
Consensus CDS ProjectCCDS23293.1
International Mouse Knockout Project StatusSpg21
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 27965 NCBI Gene Model | MGI Sequence Detail 27534 C57BL/6J ±  kb
transcript NM_138584 RefSeq | MGI Sequence Detail 2690 C57BL/6 
polypeptide Q9CQC8 UniProt | EBI | MGI Sequence Detail 308 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(224 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026151 Maspardin
Protein Ontology PR:000015519 maspardin
Graphical View of Protein Domain Structure
References (Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)
Other
accession IDs
MGD-MRK-34096, MGI:2143397

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory