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Sco1
Gene Detail
 Symbol
Name
ID
Sco1
SCO cytochrome oxidase deficient homolog 1 (yeast)
MGI:106362
Synonyms 2610001C07Rik, D11Bwg1310e
Feature Type protein coding gene
Genetic Map
Chromosome 11
40.59 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:67052670-67067070 bp, + strand
From VEGA annotation of GRCm38

  14401 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3374  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: SCO1 protein
Gene Tree: Sco1

Human
homologs
Human Homolog SCO1, SCO1 cytochrome c oxidase assembly protein
NCBI Gene ID 6341
neXtProt AC  NX_O75880
Human Synonyms  SCOD1
Human Chr (Location)  17p13.1; chr17:10680332-10697568 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from APF )
Interactions
Sco1 interacts with 224 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cellular copper ion homeostasis, copper ion transport, ...
Component mitochondrial inner membrane, mitochondrion, ...
Function copper ion binding, metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (31)    Tissues (23)    Images (5)
Theiler Stages: 4, 22, 23, 28
Assay TypeResults
Immunohistochemistry 16
RNA in situ 5
Northern blot 10
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000005911 (Evidence)
Ensembl Gene ModelENSMUSG00000069844 (Evidence)
Entrez Gene52892 (Evidence)
DFCITC1597693, TC1601020, TC1603800
DoTSDT.40141382, DT.99648121
NIA Mouse Gene IndexU012775
Consensus CDS ProjectCCDS36183.1
International Mouse Knockout Project StatusSco1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005911 VEGA Gene Model | MGI Sequence Detail 14401 C57BL/6J ±  kb
transcript OTTMUST00000013162 VEGA | MGI Sequence Detail 2186 Not Applicable 
polypeptide OTTMUSP00000006110 VEGA | MGI Sequence Detail 289 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(75 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003782 Copper chaperone SCO1/SenC
InterPro IPR017276 Synthesis of cytochrome c oxidase, Sco1/Sco2
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000014531 protein SCO1, mitochondrial
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGD-MRK-34054, MGI:1914354

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory