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Cyp3a16
Gene Detail
 Symbol
Name
ID
Cyp3a16
cytochrome P450, family 3, subfamily a, polypeptide 16
MGI:106099
Feature Type protein coding gene
Genetic Map
Chromosome 5
85.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:145436309-145469723 bp, - strand
From VEGA annotation of GRCm38

  33415 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133568  Vertebrate Homology Class
1 human; 5 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: cytochrome P450 CYP3A5
Gene Tree: Cyp3a16

Human
homologs
Human Homolog CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5
NCBI Gene ID 1577
neXtProt AC  NX_P20815
Human Synonyms  CP35, CYPIIIA5, P450PCN3, PCN3
Human Chr (Location)  7q21.1; chr7:99648190-99679998 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP3A5
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Cyp3a16 (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp3a16 interacts with 62 markers (Mir20a, Mir22, Mir29a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process demethylation, oxidation-reduction process
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function aromatase activity, demethylase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (19)    Tissues (12)   
Theiler Stages: 23, 26, 28
Assay TypeResults
Nuclease S1 19
cDNA source data(3)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(9) Genomic(6) cDNA(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025125 (Evidence)
Ensembl Gene ModelENSMUSG00000038656 (Evidence)
Entrez Gene13114 (Evidence)
UniGene378905
DoTSDT.94373359
EC1.14.14.1
Consensus CDS ProjectCCDS19862.1
International Mouse Knockout Project StatusCyp3a16
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025125 VEGA Gene Model | MGI Sequence Detail 33415 C57BL/6J ±  kb
transcript OTTMUST00000061807 VEGA | MGI Sequence Detail 1730 Not Applicable 
polypeptide OTTMUSP00000030399 VEGA | MGI Sequence Detail 504 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(196 from dbSNP Build 137)    SNPs within 2kb including multiple locations(198)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR008072 Cytochrome P450, E-class, CYP3A
InterPro IPR002402 Cytochrome P450, E-class, group II
Protein Ontology PR:000006243 cytochrome P450 3A16
References (Earliest) J:22655 Itoh S, et al., A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver. Eur J Biochem. 1994 Dec 15;226(3):877-82
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)
Other
accession IDs
MGD-MRK-33786

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory