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G6pd2 Gene Detail
Summary
  • Symbol
    G6pd2
  • Name
    glucose-6-phosphate dehydrogenase 2
  • Synonyms
    G6pdx-ps1, Gpd2, Gpd-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:105977
    NCBI Gene: 14380
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr5:61808843-61810477 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 31.99 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    30 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105977
protein coding gene Chr5:61808816-61811163 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029559
protein coding gene Chr5:61321696-61324043 (+)
A/J MGP_AJ_G0029527
protein coding gene Chr5:58979475-58981815 (+)
AKR/J MGP_AKRJ_G0029475
protein coding gene Chr5:60852911-60855251 (+)
BALB/cJ MGP_BALBcJ_G0029536
protein coding gene Chr5:59658763-59661111 (+)
C3H/HeJ MGP_C3HHeJ_G0029259
protein coding gene Chr5:61193897-61196245 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029990
protein coding gene Chr5:63890846-63893193 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027230
protein coding gene Chr5:55263183-55265545 (+)
CAST/EiJ MGP_CASTEiJ_G0028667
protein coding gene Chr5:60292691-60295039 (+)
CBA/J MGP_CBAJ_G0029228
protein coding gene Chr5:65871774-65874114 (+)
DBA/2J MGP_DBA2J_G0029374
protein coding gene Chr5:59052529-59054877 (+)
FVB/NJ MGP_FVBNJ_G0029334
protein coding gene Chr5:58258303-58260643 (+)
LP/J MGP_LPJ_G0029459
protein coding gene Chr5:61774985-61777332 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029362
protein coding gene Chr5:68579727-68582067 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030023
protein coding gene Chr5:60594934-60597281 (+)
PWK/PhJ MGP_PWKPhJ_G0028391
protein coding gene Chr5:58074370-58076831 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028225
protein coding gene Chr5:59950928-59953290 (+)
WSB/EiJ MGP_WSBEiJ_G0028748
protein coding gene Chr5:60752844-60755192 (+)



Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14380 NCBI Gene Model | MGI Sequence Detail 1635 C57BL/6J ±  kb
    transcript NM_019468 RefSeq | MGI Sequence Detail 1635 Not Specified  
    polypeptide P97324 UniProt | EBI | MGI Sequence Detail 513 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • EC
    • InterPro Domains
      IPR001282 Glucose-6-phosphate dehydrogenase
      IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal
      IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding
      IPR036291 NAD(P)-binding domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 4
      cDNA 9
      Primer pair 3
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-10222, MGD-MRK-10224, MGD-MRK-33657, MGI:893585
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 21
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    10/15/2019
    MGI 6.14
    The Jackson Laboratory