Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables glucose-6-phosphate dehydrogenase activity. Predicted to be involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; negative regulation of protein glutathionylation; and pentose-phosphate shunt, oxidative branch. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in several cellular components, including centriolar satellite; cytoplasmic side of plasma membrane; and intracellular membrane-bounded organelle. Predicted to be active in cytosol. Is expressed in genitourinary system; nervous system; and nose. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cerebrovascular disease; favism; malaria (multiple); and neonatal jaundice. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase).