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Npy4r
Gene Detail
 Symbol
Name
ID
Npy4r
neuropeptide Y receptor Y4
MGI:105374
Synonyms NYYR-D, Ppyr1, Y4
Feature Type protein coding gene
Genetic Map
Chromosome 14
20.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:34145646-34152419 bp, - strand
From NCBI annotation of GRCm38

  6774 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38119  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: neuropeptide Y receptor 1/4/6
Gene Tree: Npy4r

Human
homologs
Human Homolog NPY4R, neuropeptide Y receptor Y4
NCBI Gene ID 5540
neXtProt AC  NX_P50391
Human Synonyms  NPY4-R, PP1, PPYR1, Y4
Human Chr (Location)  10q11.2; chr10:46461099-46465881 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Mice homozygous for a null allele exhibit decreased weight, increased drinking behavior, decreased food intake, aggression towards other mice, decreased white adipose tissue, and accelerated lobuloalveolar development during pregnancy.
 
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process G-protein coupled receptor signaling pathway, neuropeptide signaling pathway, ...
Component integral component of membrane, membrane, ...
Function G-protein coupled receptor activity, neuropeptide Y receptor activity, ...
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(12) Genomic(4) cDNA(7) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000048337 (Evidence)
Entrez Gene19065 (Evidence)
UniGene57059
DFCITC1588903
DoTSDT.91295213
NIA Mouse Gene IndexU035402
Consensus CDS ProjectCCDS26933.1
International Mouse Knockout Project StatusNpy4r
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19065 NCBI Gene Model | MGI Sequence Detail 6774 C57BL/6J ±  kb
transcript NM_008919 RefSeq | MGI Sequence Detail 1903 Not Specified 
polypeptide Q61041 UniProt | EBI | MGI Sequence Detail 375 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(152 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001933 Neuropeptide Y4 receptor
InterPro IPR000611 Neuropeptide Y receptor family
Protein Ontology PR:000001623 neuropeptide Y receptor 4
Graphical View of Protein Domain Structure
References (Earliest) J:31619 Gregor P, et al., Cloning and characterization of a novel receptor to pancreatic polypeptide, a member of the neuropeptide Y receptor family. FEBS Lett. 1996 Feb 26;381(1-2):58-62
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(44)
Other
accession IDs
MGD-MRK-33043

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory