Npy4r Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Npy4r
neuropeptide Y receptor Y4
MGI:105374

32 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lep^ob/Lep⁺ Npy4r^tm1.1Hhz/Npy4r^tm1.1Hhz involves: 129X1/SvJ * C57BL/6	increased body weight	J:76479
	increased white adipose tissue amount	J:76479
Lep^ob/Lep^ob Npy4r^tm1.1Hhz/Npy4r^tm1.1Hhz involves: 129X1/SvJ * C57BL/6	abnormal adipose tissue amount	J:76479
	abnormal branching of the mammary ductal tree	J:76479
	abnormal circulating testosterone level	J:76479
	abnormal estrous cycle	J:76479
	abnormal ovarian follicle morphology	J:76479
	abnormal vagina orifice morphology	J:76479
	enhanced fertility	J:76479
	normal homeostasis/metabolism phenotype	J:76479
	increased circulating corticosterone level	J:76479
	increased Leydig cell number	J:76479
	increased seminal vesicle weight	J:76479
	increased sperm number	J:76479
	increased susceptibility to weight gain	J:76479
Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz Npy4r^tm1.1Hhz/Npy4r^tm1.1Hhz involves: 129X1/SvJ * BALB/cJ * C57BL/6	abnormal bone mineralization	J:84570
	abnormal bone ossification	J:84570
	abnormal bone structure	J:84570
	abnormal circulating pancreatic peptide level	J:84570
	abnormal eating behavior	J:84570
	abnormal osteoblast physiology	J:84570
	abnormal trabecular bone morphology	J:84570
	decreased body weight	J:84570
	decreased brown adipose tissue amount	J:84570
	decreased circulating insulin level	J:84570
	decreased circulating leptin level	J:84570
	decreased compact bone thickness	J:84570
	decreased white adipose tissue amount	J:84570
	increased trabecular bone thickness	J:84570
Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz Npy4r^tm1.1Hhz/Npy4r^tm1.1Hhz involves: 129X1/SvJ * C57BL/6	abnormal testosterone level	J:129609
	increased circulating insulin-like growth factor I level	J:129609
	increased growth hormone level	J:129609

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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