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Il13ra1
Gene Detail
 Symbol
Name
ID
Il13ra1
interleukin 13 receptor, alpha 1
MGI:105052
Synonyms CD213a1
Feature Type protein coding gene
Genetic Map
Chromosome X
20.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
ChrX:36112110-36171259 bp, + strand
From VEGA annotation of GRCm38

  59150 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1198  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Il13ra1

Human
homologs
Human Homolog IL13RA1, interleukin 13 receptor, alpha 1
NCBI Gene ID 3597
neXtProt AC  NX_P78552
Human Synonyms  CD213A1, IL-13Ra, NR4
Human Chr (Location)  Xq24; chrX:118727551-118794533 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
 
Mice homozygous for a null allele exhibit enhanced Th2 response, decreased susceptibility to parasitic infection and decreased airway hyperreactivity.
 
Interactions
Il13ra1 interacts with 322 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process interleukin-13-mediated signaling pathway
Component integral component of membrane, membrane
Function cytokine receptor activity, interleukin-13 receptor activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (80)    Tissues (23)    Images (22)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 78
RT-PCR 2
cDNA source data(32)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(36) Genomic(1) cDNA(32) Primer pair(3)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000017214 (Evidence)
Ensembl Gene ModelENSMUSG00000017057 (Evidence)
Entrez Gene16164 (Evidence)
UniGene24208
DFCITC1577689
DoTSDT.101408091, DT.527701
NIA Mouse Gene IndexU019774
Consensus CDS ProjectCCDS30057.1
International Mouse Knockout Project StatusIl13ra1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017214 VEGA Gene Model | MGI Sequence Detail 59150 C57BL/6J ±  kb
transcript OTTMUST00000041683 VEGA | MGI Sequence Detail 3712 Not Applicable 
polypeptide OTTMUSP00000018722 VEGA | MGI Sequence Detail 424 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(5)
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(104 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR015321 Interleukin-6 receptor alpha chain, binding
InterPro IPR003532 Short hematopoietin receptor, family 2, conserved site
Protein Ontology PR:000001371 interleukin-13 receptor subunit alpha-1
References (Earliest) J:30615 Hilton DJ, et al., Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):497-501
(Latest) J:209079 Dhakal M, et al., IL-13Ralpha1 is a surface marker for M2 macrophages influencing their differentiation and function. Eur J Immunol. 2014 Mar;44(3):842-55
All references(54)
Other
accession IDs
MGD-MRK-32091, MGI:2147937

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory