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Il13ra1 Gene Detail
Summary
  • Symbol
    Il13ra1
  • Name
    interleukin 13 receptor, alpha 1
  • Synonyms
    CD213a1
  • Feature Type
    protein coding gene
  • IDs
    MGI:105052
    NCBI Gene: 16164
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:36112110-36171259 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 20.49 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    104 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105052
protein coding gene ChrX:36112108-36171262 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035616
protein coding gene ChrX:31004908-31064054 (+)
A/J MGP_AJ_G0035593
protein coding gene ChrX:31108396-31167778 (+)
AKR/J MGP_AKRJ_G0035526
protein coding gene ChrX:31749887-31812653 (+)
BALB/cJ MGP_BALBcJ_G0035586
protein coding gene ChrX:30842245-30901635 (+)
C3H/HeJ MGP_C3HHeJ_G0035304
protein coding gene ChrX:31332941-31393115 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036122
protein coding gene ChrX:31622629-31683379 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032984
protein coding gene ChrX:29248691-29310329 (+)
CAST/EiJ MGP_CASTEiJ_G0034595
protein coding gene ChrX:19485668-19546407 (+)
CBA/J MGP_CBAJ_G0035273
protein coding gene ChrX:32479637-32541667 (+)
DBA/2J MGP_DBA2J_G0035425
protein coding gene ChrX:30932234-30992126 (+)
FVB/NJ MGP_FVBNJ_G0035371
protein coding gene ChrX:30688965-30748500 (+)
LP/J MGP_LPJ_G0035507
protein coding gene ChrX:31372759-31431999 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035415
protein coding gene ChrX:32940678-33002286 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036129
protein coding gene ChrX:30972374-31037213 (+)
PWK/PhJ MGP_PWKPhJ_G0034296
protein coding gene ChrX:18987574-19047942 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034137
protein coding gene ChrX:19979352-20039359 (+)
WSB/EiJ MGP_WSBEiJ_G0034730
protein coding gene ChrX:30785528-30844625 (+)



Homology
more
  • Human Ortholog
    IL13RA1, interleukin 13 receptor subunit alpha 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IL13RA1, interleukin 13 receptor subunit alpha 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CD213A1, CT19, IL-13Ra, NR4
  • Links
    NCBI Gene ID: 3597
    neXtProt AC: NX_P78552
    UniProt: P78552

  • Chr Location
    Xq24; chrX:118726954-118794533 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotypes from 2 alleles in 2 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit enhanced Th2 response, decreased susceptibility to parasitic infection and decreased airway hyperreactivity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000017057 Ensembl Gene Model | MGI Sequence Detail 59150 C57BL/6J ±  kb
    transcript ENSMUST00000033418 Ensembl | MGI Sequence Detail 3712 Not Applicable  
    polypeptide ENSMUSP00000033418 Ensembl | MGI Sequence Detail 424 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 37
      Genomic 1
      cDNA 33
      Primer pair 3

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGD-MRK-32091, MGI:2147937
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 19
    • Earliest
      J:30615 Hilton DJ, et al., Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):497-501
    • Latest
      J:257894 Rachmin I, et al., Soluble interleukin-13ralpha1: a circulating regulator of glucose. Am J Physiol Endocrinol Metab. 2017 Dec 1;313(6):E663-E671

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory