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Adora3
Gene Detail
Symbol

Name
ID
Adora3
adenosine A3 receptor
MGI:104847
Synonyms
1700001D09Rik, 4930578J19Rik, A3AR, A3R, AA3R, ARA3, Gpcr 2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
46.45 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr3:105904421-105908928 bp, + strand
From NCBI annotation of GRCm38

  4508 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:550  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 3 western clawed frog; 1 zebrafish

HCOP human homology predictions: ADORA3
Protein SuperFamily: adenosine receptor
Gene Tree: Adora3

Human
homologs
ADORA3, adenosine A3 receptor
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 140
neXtProt AC: NX_P0DMS8

Human Synonyms: A3AR

Human Chr (Location): 1p13.2; chr1:111499429-111504121 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for targeted mutations that inactivate the gene are phenotypically indistinguishable from wild-type mice.
 
Interactions
Adora3 interacts with 156 markers (Mir7-1, Mir24-1, Mir24-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (15)    Tissues (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 15
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000000562 (Evidence)
Entrez Gene 11542 (Evidence)
DFCI TC1586345, TC1688137
DoTS DT.99848288
Consensus CDS Project CCDS17712.1
International Mouse Phenotyping Consortium Status Adora3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 11542 NCBI Gene Model | MGI Sequence Detail 4508 C57BL/6J ±  kb
transcript NM_009631 RefSeq | MGI Sequence Detail 2372 C57BL/6 
polypeptide NP_033761 RefSeq | MGI Sequence Detail 319 C57BL/6 

For the selected sequences
All sequences(17) RefSeq(3)
Polymorphisms
RFLP(2) : SNPs within 2kb(379 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000001578 adenosine receptor A3
References
(Earliest) J:15563 Wilkie TM, et al., Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors. Genomics. 1993 Nov;18(2):175-84
(Latest) J:204608 Zhou X, et al., A1 adenosine receptor negatively modulates coronary reactive hyperemia via counteracting A2A-mediated H2O2 production and KATP opening in isolated mouse hearts. Am J Physiol Heart Circ Physiol. 2013 Dec 1;305(11):H1668-79
All references(73)
Other
accession IDs
MGD-MRK-16343, MGD-MRK-28143, MGI:1916546, MGI:1923096, MGI:99563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory