Adora3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adora3
adenosine A3 receptor
MGI:104847

14 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adora3^tm1Jbsn/Adora3^tm1Jbsn B6.129P2-Adora3^tm1Jbsn	abnormal mast cell degranulation	J:123463
	abnormal response/metabolism to endogenous compounds	J:123463
	decreased airway responsiveness	J:123463
	decreased circulating creatinine level	J:82054
	decreased susceptibility to kidney reperfusion injury	J:82054
	impaired neutrophil recruitment	J:123463
	ocular hypotension	J:78723
Adora3^tm1Jbsn/Adora3^tm1Jbsn either: (involves: 129P2/OlaHsd * C57BL/6 * DBA/2) or (involves: 129P2/OlaHsd * C57BL/6)	abnormal mast cell physiology	J:60293
	decreased tumor necrosis factor secretion	J:60293
Adora3^tm1Jbsn/Adora3^tm1Jbsn involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal nociception after inflammation	J:120442
	abnormal response/metabolism to endogenous compounds	J:61026, J:77069
	decreased acute inflammation	J:120442
	decreased myocardial infarct size	J:103737
	decreased systemic arterial blood pressure	J:61026
	increased coronary flow rate	J:77069

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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