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Fdxr
Gene Detail
Symbol

Name
ID
Fdxr
ferredoxin reductase
MGI:104724
Feature Type
protein coding gene
Genetic Map
Chromosome 11
80.84 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:115268024-115277050 bp, - strand
From VEGA annotation of GRCm38

  9027 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3033  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FDXR
Protein SuperFamily: ferredoxin--NADP(+) reductase
Gene Tree: Fdxr

Human
homologs
FDXR, ferredoxin reductase
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 2232
neXtProt AC: NX_P22570

Human Synonyms: ADXR

Human Chr (Location): 17q25.1; chr17:74862497-74873031 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Fdxr interacts with 21 markers (Mir207, Mir324, Mir325, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cholesterol metabolic process, lipid metabolic process, ...
Component cytoplasm, mitochondrial inner membrane, ...
Function NADPH-adrenodoxin reductase activity, NADPH binding, ...
External Resources: FuncBase
Expression
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fdxr    NEW 
Molecular
reagents
All nucleic(24) cDNA(24)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000003745 (Evidence)
Ensembl Gene Model ENSMUSG00000018861 (Evidence)
Entrez Gene 14149 (Evidence)
UniGene 4719
DFCI TC1580006
DoTS DT.527657
NIA Mouse Gene Index U033613
EC 1.18.1.6
Consensus CDS Project CCDS25625.1
International Mouse Phenotyping Consortium Status Fdxr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003745 VEGA Gene Model | MGI Sequence Detail 9027 C57BL/6J ±  kb
transcript OTTMUST00000008170 VEGA | MGI Sequence Detail 1948 Not Applicable 
polypeptide OTTMUSP00000003980 VEGA | MGI Sequence Detail 494 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(5) UniProt(4)
Polymorphisms
SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR021163 Adrenodoxin-NADP+ reductase
InterPro IPR016040 NAD(P)-binding domain
Protein Ontology PR:000007452 NADPH:adrenodoxin oxidoreductase, mitochondrial
References
(Earliest) J:29794 Itoh S, et al., cDNA cloning of mouse ferredoxin reductase from kidney. Biochim Biophys Acta. 1995 Nov 7;1264(2):159-62
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(31)
Other
accession IDs
MGD-MRK-27087

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory