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Fdxr Gene Detail
Summary
  • Symbol
    Fdxr
  • Name
    ferredoxin reductase
  • Feature Type
    protein coding gene
  • IDs
    MGI:104724
    NCBI Gene: 14149
  • Gene Overview
    MyGene.info: FDXR
Location & Maps
more
  • Sequence Map
    Chr11:115268024-115277050 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9027 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.84 cM, cytoband E2
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    FDXR, ferredoxin reductase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FDXR, ferredoxin reductase
    Orthology source: HomoloGene
  • Synonyms
    ADXR
  • Links
    NCBI Gene ID: 2232
    neXtProt AC: NX_P22570

  • Chr Location
    17q25.1; chr17:74862497-74873031 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from multigenic genotypes
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003745 VEGA Gene Model | MGI Sequence Detail 9027 C57BL/6J ±  kb
transcript OTTMUST00000008170 VEGA | MGI Sequence Detail 1948 Not Applicable  
polypeptide OTTMUSP00000003980 VEGA | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    100 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000007452 NADPH:adrenodoxin oxidoreductase, mitochondrial
  • EC
  • InterPro Domains
    IPR023753 FAD/NAD(P)-binding domain
    IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type
    IPR016040 NAD(P)-binding domain
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-27087
References
more
  • Summaries
    All 28
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:29794 Itoh S, et al., cDNA cloning of mouse ferredoxin reductase from kidney. Biochim Biophys Acta. 1995 Nov 7;1264(2):159-62
  • Latest
    J:222308 Fairfield H, et al., Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Genome Res. 2015 Jul;25(7):948-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory