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Fdxr Gene Detail
Summary
  • Symbol
    Fdxr
  • Name
    ferredoxin reductase
  • Feature Type
    protein coding gene
  • IDs
    MGI:104724
    NCBI Gene: 14149
  • Gene Overview
    MyGene.info: FDXR
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:115268024-115277050 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.84 cM, cytoband E2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104724
protein coding gene Chr11:115268024-115277102 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019377
protein coding gene Chr11:119273530-119283903 (-)
A/J MGP_AJ_G0019346
protein coding gene Chr11:114070392-114079423 (-)
AKR/J MGP_AKRJ_G0019316
protein coding gene Chr11:117470569-117479611 (-)
BALB/cJ MGP_BALBcJ_G0019320
protein coding gene Chr11:114486869-114495906 (-)
C3H/HeJ MGP_C3HHeJ_G0019126
protein coding gene Chr11:117824652-117833689 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019770
protein coding gene Chr11:122917224-122926287 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017393
protein coding gene Chr11:111111793-111120944 (-)
CAST/EiJ MGP_CASTEiJ_G0018681
protein coding gene Chr11:119135796-119144878 (-)
CBA/J MGP_CBAJ_G0019098
protein coding gene Chr11:127764358-127773389 (-)
DBA/2J MGP_DBA2J_G0019209
protein coding gene Chr11:113509082-113518580 (-)
FVB/NJ MGP_FVBNJ_G0019201
protein coding gene Chr11:112980984-112990005 (-)
LP/J MGP_LPJ_G0019279
protein coding gene Chr11:119657841-119669482 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019234
protein coding gene Chr11:126942063-126952782 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019808
protein coding gene Chr11:118133447-118142483 (-)
PWK/PhJ MGP_PWKPhJ_G0018445
protein coding gene Chr11:114786798-114795870 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018238
protein coding gene Chr11:117875001-117883981 (-)
WSB/EiJ MGP_WSBEiJ_G0018733
protein coding gene Chr11:118077929-118086965 (-)



Homology
more
  • Human Ortholog
    FDXR, ferredoxin reductase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FDXR, ferredoxin reductase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADXR, ANOA
  • Links
    NCBI Gene ID: 2232
    neXtProt AC: NX_P22570
    UniProt: P22570

  • Chr Location
    17q25.1; chr17:74862497-74873031 (-)  GRCh38.p7

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from multigenic genotypes
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018861 Ensembl Gene Model | MGI Sequence Detail 9027 C57BL/6J ±  kb
transcript ENSMUST00000021078 Ensembl | MGI Sequence Detail 1948 Not Applicable  
polypeptide ENSMUSP00000021078 Ensembl | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 1
    cDNA 24

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-27087
References
more
  • Summaries
    All 33
    Diseases 1
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:29794 Itoh S, et al., cDNA cloning of mouse ferredoxin reductase from kidney. Biochim Biophys Acta. 1995 Nov 7;1264(2):159-62
  • Latest
    J:247931 Peng Y, et al., Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy. Hum Mol Genet. 2017 Dec 15;26(24):4937-4950

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory