Fdxr Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fdxr
ferredoxin reductase
MGI:104724

33 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fdxr^em1(IMPC)Bay/Fdxr^em1(IMPC)Bay C57BL/6N-Fdxr^em1(IMPC)Bay/BayMmucd	preweaning lethality, complete penetrance	J:211773
Fdxr^tm1Xch/Fdxr⁺ B6.Cg-Fdxr^tm1Xch	abnormal iron homeostasis	J:244082
	abnormal iron level	J:244082
	abnormal mitochondrial morphology	J:244082
	abnormal protein level	J:244082
	chronic liver inflammation	J:244082
	decreased cell death	J:244082
	hepatic steatosis	J:244082
	increased alpha-fetoprotein level	J:244082
	increased B cell derived lymphoma incidence	J:244082
	increased fibroblast proliferation	J:244082
	increased hemangioma incidence	J:244082
	increased hemangiosarcoma incidence	J:244082
	increased hepatocellular carcinoma incidence	J:244082
	increased liver iron level	J:244082
	increased liver tumor incidence	J:244082
	increased lung carcinoma incidence	J:244082
	increased lymphoma incidence	J:244082
	increased myeloid sarcoma incidence	J:244082
	increased plasmacytoma incidence	J:244082
	increased sarcoma incidence	J:244082
	increased T cell derived lymphoma incidence	J:244082
	increased tumor incidence	J:244082
	premature death	J:244082
Fdxr^tm1Xch/Fdxr^tm1Xch B6.Cg-Fdxr^tm1Xch	abnormal embryo development	J:244082
	abnormal embryonic epiblast morphology	J:244082
	abnormal embryonic tissue morphology	J:244082
	abnormal extraembryonic ectoderm morphology	J:244082
	abnormal extraembryonic endoderm morphology	J:244082
	abnormal extraembryonic tissue morphology	J:244082
	abnormal iron level	J:244082
	abnormal mesoderm morphology	J:244082
	abnormal visceral endoderm morphology	J:244082
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:244082

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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