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Fgf9
Gene Detail
Symbol

Name
ID
Fgf9
fibroblast growth factor 9
MGI:104723
Synonyms
Eks, glia activating factor
Feature Type
protein coding gene
Genetic Map
Chromosome 14
30.51 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr14:58070547-58112337 bp, + strand
From VEGA annotation of GRCm38

  41791 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1523  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: fibroblast growth factor
Gene Tree: Fgf9

Human
homologs
Human Homolog FGF9, fibroblast growth factor 9
NCBI Gene ID 2254
neXtProt AC  NX_P31371
Human Synonyms  FGF-9, GAF, HBFG-9, HBGF-9, SYNS3
Human Chr (Location)  13q11-q12; chr13:21671076-21704501 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human FGF9
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Chemically induced (ENU)(1) Spontaneous(1) Targeted(7)
Incidental mutations (data from Mutagenetix )
 
Homozygotes for a targeted null mutation exhibit reduced size, pulmonary hypoplasia, cardiac dilation, impaired testes development resulting in male-to-female sex reversal, abnormal retina, and neonatal lethality.
 
Phenotype Images(3)
Interactions
Fgf9 interacts with 321 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (61 annotations)
Process angiogenesis, cardiac left ventricle morphogenesis, ...
Component basement membrane, cell, ...
Function fibroblast growth factor receptor binding, growth factor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (122 records)
Data Summary: Results (393)    Tissues (324)    Images (55)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 270
RT-PCR 123
cDNA source data(31)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(47) cDNA(35) Primer pair(9) Other(3)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000036883 (Evidence)
Ensembl Gene ModelENSMUSG00000021974 (Evidence)
Entrez Gene14180 (Evidence)
UniGene8846
DFCITC1589976, TC1699573
DoTSDT.40158105, DT.40161358, DT.486271, DT.91321776
NIA Mouse Gene IndexU015703, U283460
Consensus CDS ProjectCCDS27164.1
International Mouse Knockout Project StatusFgf9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036883 VEGA Gene Model | MGI Sequence Detail 41791 C57BL/6J ±  kb
transcript OTTMUST00000094754 VEGA | MGI Sequence Detail 1593 Not Applicable 
polypeptide OTTMUSP00000052767 VEGA | MGI Sequence Detail 208 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(6) UniProt(6)
Polymorphisms
RFLP(2) : SNPs within 2kb(135 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008996 Cytokine, IL-1-like
InterPro IPR002209 Heparin-binding growth factor/Fibroblast growth factor
Protein Ontology PR:000007500 fibroblast growth factor 9
References
(Earliest) J:35382 Miyamoto M, et al., Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property. Mol Cell Biol. 1993 Jul;13(7):4251-9
(Latest) J:209131 Saba R, et al., CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81
All references(191)
Other
accession IDs
MGD-MRK-27086, MGI:2182125

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory