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Pla2g2a
Gene Detail
Symbol

Name
ID
Pla2g2a
phospholipase A2, group IIA (platelets, synovial fluid)
MGI:104642
Synonyms
EF, Enhancing factor, modifier of Min1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
70.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(15)
Sequence Map
Chr4:138831860-138835186 bp, + strand
From VEGA annotation of GRCm38

  3327 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: phospholipase A2
Gene Tree: Pla2g2a
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Spontaneous(2)
 
Mutations in this gene influence susceptibility to intestinal adenomas.
 
Interactions
Pla2g2a interacts with 1 marker (Mir92-2)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process lipid catabolic process, lipid metabolic process, ...
Component membrane, mitochondrion
Function calcium ion binding, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (148)    Tissues (139)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 8
RT-PCR 46
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(32) Genomic(6) cDNA(23) Primer pair(3)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000010068 (Evidence)
Ensembl Gene ModelENSMUSG00000058908 (Evidence)
Entrez Gene18780 (Evidence)
UniGene4675
DFCITC1576245
DoTSDT.526216, DT.55117856
NIA Mouse Gene IndexU005006
EC3.1.1.4
International Mouse Knockout Project StatusPla2g2a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010068 VEGA Gene Model | MGI Sequence Detail 3327 C57BL/6J ±  kb
transcript OTTMUST00000023407 VEGA | MGI Sequence Detail 788 Not Applicable 
polypeptide OTTMUSP00000063758 VEGA | MGI Sequence Detail 147 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(4) UniProt(5)
Polymorphisms
All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs within 2kb(69 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001211 Phospholipase A2
InterPro IPR013090 Phospholipase A2, active site
InterPro IPR016090 Phospholipase A2 domain
Protein Ontology PR:000012799 phospholipase A2, membrane associated
References
(Earliest) J:1879 Moser AR, et al., The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system. J Cell Biol. 1992 Mar;116(6):1517-26
(Latest) J:181418 Wei Y, et al., sPLA2-IIa amplifies ocular surface inflammation in the experimental dry eye (DE) BALB/c mouse model. Invest Ophthalmol Vis Sci. 2011 Jun;52(7):4780-8
All references(92)
Other
accession IDs
MGD-MRK-12352, MGD-MRK-26080, MGI:97049

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory