Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable calcium ion binding activity; calcium-dependent phospholipase A2 activity; and phospholipid binding activity. Involved in defense response to Gram-positive bacterium; intestinal stem cell homeostasis; and prostaglandin biosynthetic process. Acts upstream of or within negative regulation of epithelial cell proliferation; regulation of endothelial cell proliferation; and somatic stem cell population maintenance. Located in mitochondrion. Is expressed in ileum; jejunum; and primary palate. Human ortholog(s) of this gene implicated in cholecystolithiasis; colorectal cancer; gastroesophageal reflux disease; and human immunodeficiency virus infectious disease. Orthologous to human PLA2G2A (phospholipase A2 group IIA).