Clec3b
Gene Detail

Symbol Name ID

Clec3b C-type lectin domain family 3, member b MGI:104540

Synonyms

Tna

Feature Type

protein coding gene

Genetic Map

Chromosome 9

73.91 cM, cytoband F1-F3
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr9:123150946-123157430 bp, + strand From Ensembl annotation of GRCm38   6485 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:31145  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 chicken; 1 zebrafish

Gene Tree: Clec3b

Human homologs

Human Homolog		CLEC3B, C-type lectin domain family 3, member B
NCBI Gene ID		7123
neXtProt AC		NX_P05452
Human Synonyms		TN, TNA
Human Chr (Location)		3p22-p21.3; chr3:45067759-45077563 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Homozygous null mice exhibit spinal deformities including kyphosis and abnormal morphology of the vertebrae.

 
Human Diseases Modeled Using Mouse Clec3b (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	bone mineralization, positive regulation of plasminogen activation, ...
Component	cytoplasm, extracellular region, ...
Function	calcium ion binding, carbohydrate binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (31)    Tissues (20)    Images (17)
Theiler Stages: 20, 22, 23, 24, 25, 26, 28

Assay Type	Results
Immunohistochemistry	8
Northern blot	11
Western blot	3
RT-PCR	9

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) Genomic(1) cDNA(12) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000025784 (Evidence)
Entrez Gene	21922 (Evidence)
UniGene	34588
DFCI	TC1584741
DoTS	DT.110589862, DT.97396516
NIA Mouse Gene Index	U011193
Consensus CDS Project	CCDS23656.1
International Mouse Knockout Project Status	Clec3b

Sequences

Length	Strain/Species
genomic	ENSMUSG00000025784	Ensembl Gene Model | MGI Sequence Detail	6485	C57BL/6J
transcript	ENSMUST00000026890	Ensembl | MGI Sequence Detail	990	Not Applicable
polypeptide	ENSMUSP00000026890	Ensembl | MGI Sequence Detail	202	Not Applicable

All sequences(17) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(1) : SNPs(55 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001304	C-type lectin
InterPro	IPR018378	C-type lectin, conserved site
InterPro	IPR016187	C-type lectin fold
InterPro	IPR016186	C-type lectin-like
Protein Ontology	PR:000005567	tetranectin

References

(Earliest) J:190010 Wewer UM, et al., A potential role for tetranectin in mineralization during osteogenesis. J Cell Biol. 1994 Dec;127(6 Pt 1):1767-75
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGD-MRK-25972