About   Help   FAQ
Clec3b Gene Detail
Summary
  • Symbol
    Clec3b
  • Name
    C-type lectin domain family 3, member b
  • Synonyms
    Tna
  • Feature Type
    protein coding gene
  • IDs
    MGI:104540
    NCBI Gene: 21922
  • Gene Overview
    MyGene.info: CLEC3B
Location & Maps
more
  • Sequence Map
    Chr9:123150946-123157430 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6485 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CLEC3B, C-type lectin domain family 3 member B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CLEC3B, C-type lectin domain family 3 member B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    TN, TNA
  • Links
    NCBI Gene ID: 7123
    neXtProt AC: NX_P05452

  • Chr Location
    3p22-p21.3; chr3:45026267-45036071 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with Clec3b mouse models

Human Disease Mouse Models
       Scheuermann Disease   OMIM: 181440 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele develop pronounced cervical lordosis and thoracic kyphosis associated with wedge-shaped deformities of the vertebrae, growth plate irregularities, and an asymmetric development of the intervertebral disks.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025784 Ensembl Gene Model | MGI Sequence Detail 6485 C57BL/6J ±  kb
transcript ENSMUST00000026890 Ensembl | MGI Sequence Detail 990 Not Applicable  
polypeptide ENSMUSP00000026890 Ensembl | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    72 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    Genomic 1
    cDNA 12
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-25972
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:190010 Wewer UM, et al., A potential role for tetranectin in mineralization during osteogenesis. J Cell Biol. 1994 Dec;127(6 Pt 1):1767-75
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory