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Clec3b
Gene Detail
 Symbol
Name
ID
Clec3b
C-type lectin domain family 3, member b
MGI:104540
Synonyms Tna
Feature Type protein coding gene
Genetic Map
Chromosome 9
73.91 cM, cytoband F1-F3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr9:123150946-123157430 bp, + strand
From Ensembl annotation of GRCm38

  6485 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31145  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 2 zebrafish

Gene Tree: Clec3b

Human
homologs
Human Homolog CLEC3B, C-type lectin domain family 3, member B
NCBI Gene ID 7123
neXtProt AC  NX_P05452
Human Synonyms  TN, TNA
Human Chr (Location)  3p22-p21.3; chr3:45026267-45036071 (+)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice exhibit spinal deformities including kyphosis and abnormal morphology of the vertebrae.
 
Human Diseases Modeled Using Mouse Clec3b (1)    Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process bone mineralization, positive regulation of plasminogen activation, ...
Component cytoplasm, extracellular region, ...
Function calcium ion binding, carbohydrate binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (31)    Tissues (20)    Images (17)
Theiler Stages: 20, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 8
Northern blot 11
Western blot 3
RT-PCR 9
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(14) Genomic(1) cDNA(12) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000025784 (Evidence)
Entrez Gene21922 (Evidence)
UniGene34588
DFCITC1584741
DoTSDT.110589862, DT.97396516
NIA Mouse Gene IndexU011193
Consensus CDS ProjectCCDS23656.1
International Mouse Knockout Project StatusClec3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025784 Ensembl Gene Model | MGI Sequence Detail 6485 C57BL/6J ±  kb
transcript ENSMUST00000026890 Ensembl | MGI Sequence Detail 990 Not Applicable 
polypeptide ENSMUSP00000026890 Ensembl | MGI Sequence Detail 202 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(73 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000005567 tetranectin
References (Earliest) J:190010 Wewer UM, et al., A potential role for tetranectin in mineralization during osteogenesis. J Cell Biol. 1994 Dec;127(6 Pt 1):1767-75
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGD-MRK-25972

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory