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Mef2b Gene Detail
Summary
  • Symbol
    Mef2b
  • Name
    myocyte enhancer factor 2B
  • Feature Type
    protein coding gene
  • IDs
    MGI:104526
    NCBI Gene: 17259
Location & Maps
more
  • Sequence Map
    Chr8:70152778-70167488 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14711 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.15 cM, cytoband C1
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    MEF2B, myocyte enhancer factor 2B
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MEF2B, myocyte enhancer factor 2B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RSRFR2
  • Links
    NCBI Gene ID: 100271849
    neXtProt AC: NX_Q02080

  • Chr Location
    19p13.11; chr19:19145567-19170289 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Mef2b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022207 VEGA Gene Model | MGI Sequence Detail 14711 C57BL/6J ±  kb
transcript OTTMUST00000052774 VEGA | MGI Sequence Detail 1342 Not Applicable  
polypeptide OTTMUSP00000025066 VEGA | MGI Sequence Detail 349 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    169 from dbSNP Build 142
  • RFLP
Molecular
Reagents
less
  • All nucleic 18
    Genomic 2
    cDNA 13
    Primer pair 3

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-25957, MGI:2142554, MGI:3779429
References
more
  • Summaries
    All 42
    Developmental Gene Expression 15
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:28136 Lyons GE, et al., Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation. J Neurosci. 1995 Aug;15(8):5727-38
  • Latest
    J:187627 She H, et al., Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response. J Neurochem. 2012 Sep;122(6):1203-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory