Mef2b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mef2b
myocyte enhancer factor 2B
MGI:104526

8 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ighg1^tm1(cre)Cgn/0 Mef2b^tm1.1Rdf/Mef2b⁺ involves: 129P2/OlaHsd * C57BL/6	decreased germinal center B cell number	J:265465
Ighg1^tm1(cre)Cgn/0 Mef2b^tm1.1Rdf/Mef2b^tm1.1Rdf involves: 129P2/OlaHsd * C57BL/6	abnormal mature B cell morphology	J:265465
	decreased germinal center B cell number	J:265465
Ighg1^tm1(cre)Cgn/0 Mef2b^tm2Rdf/Mef2b⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal mature B cell morphology	J:265465
	increased germinal center B cell number	J:265465
Ighg1^tm1(cre)Cgn/0 Mef2b^tm2Rdf/Mef2b^tm1.1Rdf involves: 129P2/OlaHsd * C57BL/6	abnormal mature B cell morphology	J:265465
	increased germinal center B cell number	J:265465
Mef2b^{tm2b(EUCOMM)Hmgu}/Mef2b^{tm2b(EUCOMM)Hmgu} C57BL/6N-Mef2b^{tm2b(EUCOMM)Hmgu}/Bay	abnormal snout morphology	J:211773
Mef2b^tm2Rdf/Mef2b⁺ Tg(Cr2-cre)3Cgn/0 involves: C57BL/6	abnormal mature B cell morphology	J:265465
	enlarged lymph nodes	J:265465
	enlarged mesenteric lymph nodes	J:265465
	enlarged spleen	J:265465
	increased B cell derived lymphoma incidence	J:265465
	increased germinal center B cell number	J:265465

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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