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Cntn2
Gene Detail
Symbol

Name
ID
Cntn2
contactin 2
MGI:104518
Synonyms
axonin, D130012K04Rik, TAG-1, Tax
Feature Type
protein coding gene
Genetic Map
Chromosome 1
57.42 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:132509427-132543256 bp, - strand
From VEGA annotation of GRCm38

  33830 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3720  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cntn2

Human
homologs
Human Homolog CNTN2, contactin 2 (axonal)
NCBI Gene ID 6900
neXtProt AC  NX_Q02246
Human Synonyms  AXT, FAME5, TAG-1, TAX, TAX1
Human Chr (Location)  1q32.1; chr1:205043212-205078043 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CNTN2
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Targeted mutation of this locus results in molecular abnormalities in the central nervous system.
 
Interactions
Cntn2 interacts with 446 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (47 annotations)
Process adult walking behavior, axonal fasciculation, ...
Component anchored component of membrane, axon, ...
Function carbohydrate binding, glycoprotein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (161 records)
Data Summary: Results (569)    Tissues (255)    Images (207)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 403
RNA in situ 160
Western blot 4
RT-PCR 2
cDNA source data(17)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(24) cDNA(19) Primer pair(1) Other(4)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000049393 (Evidence)
Ensembl Gene ModelENSMUSG00000053024 (Evidence)
Entrez Gene21367 (Evidence)
DFCITC1572786, TC1597410, TC1575706
DoTSDT.103565143, DT.99853522, DT.99849833, DT.91589728, DT.91279904, DT.40138283
NIA Mouse Gene IndexU021763, U197527
Consensus CDS ProjectCCDS15288.1
International Mouse Knockout Project StatusCntn2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049393 VEGA Gene Model | MGI Sequence Detail 33830 C57BL/6J ±  kb
transcript OTTMUST00000125915 VEGA | MGI Sequence Detail 7177 Not Applicable 
polypeptide OTTMUSP00000068144 VEGA | MGI Sequence Detail 1040 Not Applicable 

For the selected sequences
All sequences(82) RefSeq(10) UniProt(11)
Polymorphisms
SNPs within 2kb(201 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013098 Immunoglobulin I-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR003598 Immunoglobulin subtype 2
Protein Ontology PR:000005667 contactin-2
References
(Earliest) J:18717 Wolfer DP, et al., Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system. J Comp Neurol. 1994 Jul 1;345(1):1-32
(Latest) J:213066 Namba T, et al., Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Neuron. 2014 Feb 19;81(4):814-29
All references(204)
Other
accession IDs
MGD-MRK-25949, MGI:2443768

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory