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Cntn2
Gene Detail
 Symbol
Name
ID
Cntn2
contactin 2
MGI:104518
Synonyms axonin, D130012K04Rik, TAG-1, Tax
Feature Type protein coding gene
Genetic Map
Chromosome 1
57.42 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:132509425-132542940 bp, - strand
From NCBI annotation of GRCm38

  33516 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3720  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cntn2

Human
homologs
Human Homolog CNTN2, contactin 2 (axonal)
NCBI Gene ID 6900
neXtProt AC  NX_Q02246
Human Synonyms  AXT, FAME5, TAG-1, TAX, TAX1
Human Chr (Location)  1q32.1; chr1:205043212-205078043 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CNTN2
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Targeted mutation of this locus results in molecular abnormalities in the central nervous system.
 
Gene Ontology
(GO)
classifications
All GO classifications: (47 annotations)
Process adult walking behavior, axonal fasciculation, ...
Component anchored component of membrane, axon, ...
Function carbohydrate binding, glycoprotein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (150 records)
Data Summary: Results (569)    Tissues (244)    Images (207)
Theiler Stages: 15, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 403
RNA in situ 160
Western blot 4
RT-PCR 2
cDNA source data(17)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(24) cDNA(19) Primer pair(1) Other(4)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000053024 (Evidence)
Entrez Gene21367 (Evidence)
DFCITC1572786, TC1575706, TC1597410
DoTSDT.103565143, DT.40138283, DT.91279904, DT.91589728, DT.99849833, DT.99853522
NIA Mouse Gene IndexU021763, U197527
Consensus CDS ProjectCCDS15288.1
International Mouse Knockout Project StatusCntn2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 21367 NCBI Gene Model | MGI Sequence Detail 33516 C57BL/6J ±  kb
transcript NM_177129 RefSeq | MGI Sequence Detail 9535 C57BL/6 
polypeptide Q61330 UniProt | EBI | MGI Sequence Detail 1040 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(10) UniProt(4)
Polymorphisms SNPs within 2kb(201 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013098 Immunoglobulin I-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR003598 Immunoglobulin subtype 2
Protein Ontology PR:000005667 contactin-2
Graphical View of Protein Domain Structure
References (Earliest) J:18717 Wolfer DP, et al., Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system. J Comp Neurol. 1994 Jul 1;345(1):1-32
(Latest) J:205567 Li K, et al., Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31
All references(191)
Other
accession IDs
MGD-MRK-25949, MGI:2443768

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory