Cyb561
Gene Detail

Symbol Name ID

Cyb561 cytochrome b-561 MGI:103253

Feature Type

protein coding gene

Genetic Map

Chromosome 11

68.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr11:105933702-105953336 bp, - strand From VEGA annotation of GRCm38   19635 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37552  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: cytochrome b561
Gene Tree: Cyb561

Human homologs

Human Homolog		CYB561, cytochrome b561
NCBI Gene ID		1534
neXtProt AC		NX_P49447
Human Synonyms		CYB561A1, FRRS2
Human Chr (Location)		17q23.3; chr17:61509665-61523722 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(11) : Targeted(2) Gene trapped(9)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	electron transport chain, oxidation-reduction process, ...
Component	cytoplasmic vesicle, integral to membrane, ...
Function	ferric-chelate reductase activity, metal ion binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (94)    Tissues (27)    Images (21)
Theiler Stages: 11, 13, 18, 23, 25, 28

Assay Type	Results
RNA in situ	83
Northern blot	11

cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(12)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000003116 (Evidence)
Ensembl Gene Model	ENSMUSG00000019590 (Evidence)
Entrez Gene	13056 (Evidence)
DFCI	TC1575821
DoTS	DT.101712792, DT.488098, DT.87050683
Consensus CDS Project	CCDS25542.1
International Mouse Knockout Project Status	Cyb561

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003116	VEGA Gene Model | MGI Sequence Detail	19635	C57BL/6J
transcript	OTTMUST00000006422	VEGA | MGI Sequence Detail	2741	Not Applicable
polypeptide	OTTMUSP00000003024	VEGA | MGI Sequence Detail	250	Not Applicable

All sequences(33) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(2) : SNPs(14 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004877	Cytochrome b561, eukaryote
InterPro	IPR006593	Cytochrome b561/ferric reductase transmembrane
Protein Ontology	PR:000006077	cytochrome b561

References

(Earliest) J:28039 Kozak CA, et al., Genetic mapping of the gene encoding cytochrome b561 to mouse chromosome 11. Mamm Genome. 1995;6:559
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Other accession IDs

MGD-MRK-24129