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Cyb561 Gene Detail
Summary
  • Symbol
    Cyb561
  • Name
    cytochrome b-561
  • Feature Type
    protein coding gene
  • IDs
    MGI:103253
    NCBI Gene: 13056
  • Gene Overview
    MyGene.info: CYB561
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:105933702-105945118 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.81 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103253
protein coding gene Chr11:105933702-105953336 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019287
protein coding gene Chr11:109195778-109215288 (-)
A/J MGP_AJ_G0019255
protein coding gene Chr11:104553303-104572722 (-)
AKR/J MGP_AKRJ_G0019224
protein coding gene Chr11:107672095-107694024 (-)
BALB/cJ MGP_BALBcJ_G0019229
protein coding gene Chr11:104958197-104978750 (-)
C3H/HeJ MGP_C3HHeJ_G0019038
protein coding gene Chr11:107970228-107990210 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019679
protein coding gene Chr11:112552927-112573011 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017304
protein coding gene Chr11:101845265-101865304 (-)
CAST/EiJ MGP_CASTEiJ_G0018591
protein coding gene Chr11:109019775-109039151 (-)
CBA/J MGP_CBAJ_G0019007
protein coding gene Chr11:117232898-117254182 (-)
DBA/2J MGP_DBA2J_G0019119
protein coding gene Chr11:104022352-104050235 (-)
FVB/NJ MGP_FVBNJ_G0019110
protein coding gene Chr11:103531663-103551938 (-)
LP/J MGP_LPJ_G0019189
protein coding gene Chr11:109650859-109671206 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019140
protein coding gene Chr11:116523918-116544981 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019716
protein coding gene Chr11:108160659-108180185 (-)
PWK/PhJ MGP_PWKPhJ_G0018356
protein coding gene Chr11:105120911-105140191 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018147
protein coding gene Chr11:107925983-107949482 (-)
WSB/EiJ MGP_WSBEiJ_G0018642
protein coding gene Chr11:108130349-108149747 (-)



Homology
more
  • Human Ortholog
    CYB561, cytochrome b561
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CYB561, cytochrome b561
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CYB561A1, FRRS2
  • Links
    NCBI Gene ID: 1534
    neXtProt AC: NX_P49447
    UniProt: P49447

  • Chr Location
    17q23.3; chr17:63432304-63446361 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    33 phenotypes from 2 alleles in 3 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 13056 NCBI Gene Model | MGI Sequence Detail 11417 C57BL/6J ±  kb
    transcript NM_001356374 RefSeq | MGI Sequence Detail 3106 C57BL/6  
    polypeptide Q60720 UniProt | EBI | MGI Sequence Detail 250 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-24129
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:28039 Kozak CA, et al., Genetic mapping of the gene encoding cytochrome b561 to mouse chromosome 11. Mamm Genome. 1995;6:559
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory