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Cyb561
Gene Detail
Symbol

Name
ID
Cyb561
cytochrome b-561
MGI:103253
Feature Type
protein coding gene
Genetic Map
Chromosome 11
68.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:105933702-105953336 bp, - strand
From VEGA annotation of GRCm38

  19635 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37552  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CYB561
Protein SuperFamily: cytochrome b561
Gene Tree: Cyb561

Human
homologs
CYB561, cytochrome b561
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 1534
neXtProt AC: NX_P49447

Human Synonyms: CYB561A1, FRRS2

Human Chr (Location): 17q23.3; chr17:63432304-63446361 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(9) Targeted(3)
Incidental mutations (data from APF )
Interactions
Cyb561 interacts with 190 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process electron transport chain, oxidation-reduction process, ...
Component cytoplasmic vesicle, integral component of membrane, ...
Function ferric-chelate reductase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (94)    Tissues (27)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 83
Northern blot 11
cDNA source data(12)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase cyb561    NEW 
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000003116 (Evidence)
Ensembl Gene Model ENSMUSG00000019590 (Evidence)
Entrez Gene 13056 (Evidence)
DFCI TC1575821
DoTS DT.101712792, DT.488098, DT.87050683
Consensus CDS Project CCDS25542.1
International Mouse Phenotyping Consortium Status Cyb561
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003116 VEGA Gene Model | MGI Sequence Detail 19635 C57BL/6J ±  kb
transcript OTTMUST00000006422 VEGA | MGI Sequence Detail 2741 Not Applicable 
polypeptide OTTMUSP00000003024 VEGA | MGI Sequence Detail 250 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(12) UniProt(7)
Polymorphisms
RFLP(2) : SNPs within 2kb(54 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR028837 Cytochrome b561
InterPro IPR004877 Cytochrome b561 domain
InterPro IPR006593 Cytochrome b561/ferric reductase transmembrane
Protein Ontology PR:000006077 cytochrome b561
References
(Earliest) J:28039 Kozak CA, et al., Genetic mapping of the gene encoding cytochrome b561 to mouse chromosome 11. Mamm Genome. 1995;6:559
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGD-MRK-24129

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory