Sequence Detail

ID/Version

Q60720 Q9D6C9 Q3TEC6 (UniProt | EBI)

Last sequence update: 2002-11-25
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Transmembrane ascorbate-dependent reductase CYB561 {ECO:0000305|PubMed:14499595, ECO:0000305|PubMed:16256064}; EC=7.2.1.3 {ECO:0000305|PubMed:14499595};AltName: Full=Chromaffin granule Cyt b561 {ECO:0000303|PubMed:16256064};

Provider

SWISS-PROT

Sequence

Polypeptide 250 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cyb561	cytochrome b-561	14	101	3	14

Sequence references in MGI

J:50408 Srivastava M, et al., Mouse cytochrome b561: cDNA cloning and expression in rat brain, mouse embryos, and human glioma cell lines. DNA Cell Biol. 1998 Sep;17(9):771-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114129 Vargas JD, et al., Stromal cell-derived receptor 2 and cytochrome b561 are functional ferric reductases. Biochim Biophys Acta. 2003 Sep 23;1651(1-2):116-23
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:302449 Berczi A, et al., Heterologous expression and site-directed mutagenesis of an ascorbate-reducible cytochrome b561. Arch Biochem Biophys. 2005 Nov 15;443(1-2):82-92
J:319827 van den Berg MP, et al., Mutations in CYB561 Causing a Novel Orthostatic Hypotension Syndrome. Circ Res. 2018 Mar 16;122(6):846-854