Cyp2c29
Gene Detail

Symbol Name ID

Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 MGI:103238

Synonyms

Ah-2, Ahh-1, AHOH, AHOHase, Cyp2c, P450-2C

Feature Type

protein coding gene

Genetic Map

Chromosome 19

33.91 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(29)

Sequence Map

Chr19:39269405-39330713 bp, + strand From VEGA annotation of GRCm38   61309 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:117948  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 chicken

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c29

Human homologs

Human Homolog		CYP2C8, cytochrome P450, family 2, subfamily C, polypeptide 8
NCBI Gene ID		1558
neXtProt AC		NX_P10632
Human Synonyms		CPC8, CYPIIC8, MP-12/MP-20
Human Chr (Location)		10q23.33; chr10:96796529-96829254 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CYP2C8

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function	aromatase activity, caffeine oxidase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)    Images (1)
Theiler Stages: 10, 18, 22, 23, 25, 28

Assay Type	Results
RNA in situ	94
RT-PCR	12

cDNA source data(13)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(19) cDNA(16) Primer pair(1) Other(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000028391 (Evidence)
Ensembl Gene Model	ENSMUSG00000003053 (Evidence)
Entrez Gene	13095 (Evidence)
DFCI	TC1576171, TC1724188, TC1762649
DoTS	DT.101340500, DT.101409931, DT.496568
EC	1.14.14.1
Consensus CDS Project	CCDS29793.1
International Mouse Knockout Project Status	Cyp2c29

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028391	VEGA Gene Model | MGI Sequence Detail	61309	C57BL/6J
transcript	OTTMUST00000070352	VEGA | MGI Sequence Detail	1783	Not Applicable
polypeptide	OTTMUSP00000035836	VEGA | MGI Sequence Detail	490	Not Applicable

All sequences(35) RefSeq(2) UniProt(4)

Polymorphisms

RFLP(8) : SNPs(299 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
InterPro	IPR008068	Cytochrome P450, E-class, group I, CYP2B-like
Protein Ontology	PR:000006225	cytochrome P450 2C29

References

(Earliest) J:84316 Niwa A, et al., Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse. Distinction between the 'responsive' homozygote and heterozygote at the Ah locus. Arch Biochem Biophys. 1975 Feb;166(2):559-64
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(56)

Other accession IDs

MGD-MRK-1200, MGD-MRK-1220, MGD-MRK-13110, MGD-MRK-2319, MGD-MRK-24113, MGI:2147480, MGI:2147488