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Azgp1
Gene Detail
 Symbol
Name
ID
Azgp1
alpha-2-glycoprotein 1, zinc
MGI:103163
Synonyms Zag
Feature Type protein coding gene
Genetic Map
Chromosome 5
76.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(11)
Sequence Map
Chr5:137981521-137990233 bp, + strand
From NCBI annotation of GRCm38

  8713 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:915  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Azgp1

Human
homologs
Human Homolog AZGP1, alpha-2-glycoprotein 1, zinc-binding
NCBI Gene ID 563
neXtProt AC  NX_P25311
Human Synonyms  ZA2G, ZAG
Human Chr (Location)  7q22.1; chr7:99966727-99976112 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit impaired lipolysis and increased body weight when fed standard food or a high fat diet.
 
Interactions
Azgp1 interacts with 59 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process antigen processing and presentation, antigen processing and presentation of peptide antigen via MHC class I, ...
Component extracellular region, extracellular space, ...
Function antigen binding, glycoprotein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (100)    Tissues (98)    Images (3)
Theiler Stages: 23, 26, 28
Assay TypeResults
RNA in situ 54
RT-PCR 46
cDNA source data(81)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(84) Genomic(1) cDNA(81) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000037053 (Evidence)
Entrez Gene12007 (Evidence)
UniGene30061
DFCITC1577826, TC1681481
DoTSDT.101400402, DT.535707, DT.97340386
NIA Mouse Gene IndexU006332
Consensus CDS ProjectCCDS19783.1
International Mouse Knockout Project StatusAzgp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12007 NCBI Gene Model | MGI Sequence Detail 8713 C57BL/6J ±  kb
transcript NM_013478 RefSeq | MGI Sequence Detail 1315 C57BL/6 
polypeptide Q64726 UniProt | EBI | MGI Sequence Detail 307 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms PCR(1) : SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003597 Immunoglobulin C1-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR011162 MHC classes I/II-like antigen recognition protein
InterPro IPR001039 MHC class I, alpha chain, alpha1/alpha2
InterPro IPR011161 MHC class I-like antigen recognition
Protein Ontology PR:000004530 zinc-alpha-2-glycoprotein
Graphical View of Protein Domain Structure
References (Earliest) J:24018 Ueyama H, et al., Structure and expression of rat and mouse mRNAs for Zn-alpha 2-glycoprotein. J Biochem. 1994 Sep;116(3):677-81
(Latest) J:182566 Russell ST, et al., Role of beta-adrenergic receptors in the anti-obesity and anti-diabetic effects of zinc-alpha2-glycoprotien (ZAG). Biochim Biophys Acta. 2012 Apr;1821(4):590-9
All references(41)
Other
accession IDs
MGD-MRK-24029

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory