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Azgp1
Gene Detail
Symbol

Name
ID
Azgp1
alpha-2-glycoprotein 1, zinc
MGI:103163
Synonyms
Zag
Feature Type
protein coding gene
Genetic Map
Chromosome 5
76.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(11)
Sequence Map
Chr5:137981520-137990233 bp, + strand
From VEGA annotation of GRCm38

  8714 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:915  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: AZGP1
Gene Tree: Azgp1

Human
homologs
AZGP1, alpha-2-glycoprotein 1, zinc-binding
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 563
neXtProt AC: NX_P25311

Human Synonyms: ZA2G, ZAG

Human Chr (Location): 7q22.1; chr7:99966727-99976112 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit impaired lipolysis and increased body weight when fed standard food or a high fat diet.
 
Interactions
Azgp1 interacts with 59 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (100)    Tissues (98)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 54
RT-PCR 46
cDNA source data(81)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(84) Genomic(1) cDNA(81) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000054656 (Evidence)
Ensembl Gene Model ENSMUSG00000037053 (Evidence)
Entrez Gene 12007 (Evidence)
UniGene 30061
DFCI TC1577826, TC1681481
DoTS DT.101400402, DT.535707, DT.97340386
NIA Mouse Gene Index U006332
Consensus CDS Project CCDS19783.1
International Mouse Phenotyping Consortium Status Azgp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000054656 VEGA Gene Model | MGI Sequence Detail 8714 C57BL/6J ±  kb
transcript OTTMUST00000135506 VEGA | MGI Sequence Detail 1297 Not Applicable 
polypeptide OTTMUSP00000071701 VEGA | MGI Sequence Detail 307 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(2)
Polymorphisms
PCR(1) : SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003597 Immunoglobulin C1-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR011162 MHC classes I/II-like antigen recognition protein
InterPro IPR027648 MHC class I alpha chain
InterPro IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
InterPro IPR011161 MHC class I-like antigen recognition-like
Protein Ontology PR:000004530 zinc-alpha-2-glycoprotein
References
(Earliest) J:24018 Ueyama H, et al., Structure and expression of rat and mouse mRNAs for Zn-alpha 2-glycoprotein. J Biochem. 1994 Sep;116(3):677-81
(Latest) J:182566 Russell ST, et al., Role of beta-adrenergic receptors in the anti-obesity and anti-diabetic effects of zinc-alpha2-glycoprotien (ZAG). Biochim Biophys Acta. 2012 Apr;1821(4):590-9
All references(41)
Other
accession IDs
MGD-MRK-24029

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory