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Pou6f1
Gene Detail
 Symbol
Name
ID
Pou6f1
POU domain, class 6, transcription factor 1
MGI:102935
Synonyms 2310038G18Rik, cns-1, Emb
Feature Type protein coding gene
Genetic Map
Chromosome 15
56.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr15:100575318-100599984 bp, - strand
From VEGA annotation of GRCm38

  24667 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7703  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Human
homologs
Human Homolog POU6F1, POU class 6 homeobox 1
NCBI Gene ID 5463
neXtProt AC  NX_Q14863
Human Synonyms  BRN5, MPOU, TCFB1
Human Chr (Location)  12q13.13; chr12:51186936-51217693 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Radiation induced(1) Targeted(2)
Genomic Mutations involving Pou6f1 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pou6f1 interacts with 295 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component nucleus
Function DNA binding, sequence-specific DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (267)    Tissues (91)    Images (45)
Theiler Stages: 17, 19, 21, 23, 28
Assay TypeResults
RNA in situ 267
cDNA source data(68)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(72) Genomic(3) cDNA(69)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000039916 (Evidence)
Ensembl Gene ModelENSMUSG00000098598 (Evidence), ENSMUSG00000009739 (Evidence)
Entrez Gene19009 (Evidence)
UniGene28825
DFCITC1587483, TC1594116, TC1597665, TC1601467, TC1606438, TC1756250
DoTSDT.101286825, DT.101735309, DT.482248, DT.490046, DT.55194006, DT.94233517
NIA Mouse Gene IndexU036668
Consensus CDS ProjectCCDS57009.1
International Mouse Knockout Project StatusPou6f1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000039916 VEGA Gene Model | MGI Sequence Detail 24667 C57BL/6J ±  kb
transcript OTTMUST00000103715 VEGA | MGI Sequence Detail 4953 Not Applicable 
polypeptide OTTMUSP00000057970 VEGA | MGI Sequence Detail 576 Not Applicable 

For the selected sequences
All sequences(96) RefSeq(20) UniProt(7)
Polymorphisms RFLP(3) : SNPs within 2kb(198 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR010982 Lambda repressor-like, DNA-binding domain
InterPro IPR013847 POU domain
InterPro IPR000327 POU-specific
Protein Ontology PR:000013046 POU domain, class 6, transcription factor 1
References (Earliest) J:3981 Dowbenko D, et al., Structure and chromosomal localization of the murine gene encoding GLYCAM 1. A mucin-like endothelial ligand for L selectin. J Biol Chem. 1993 Feb 25;268(6):4525-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)
Other
accession IDs
MGD-MRK-23769, MGI:1914205, MGI:2146292

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory