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Pou6f1 Gene Detail
Summary
  • Symbol
    Pou6f1
  • Name
    POU domain, class 6, transcription factor 1
  • Synonyms
    2310038G18Rik, cns-1, Emb
  • Feature Type
    protein coding gene
  • IDs
    MGI:102935
    NCBI Gene: 19009
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:100473199-100497865 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.35 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102935
protein coding gene Chr15:100473199-100497949 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022355
protein coding gene Chr15:102546454-102579127 (-)
A/J MGP_AJ_G0022317
protein coding gene Chr15:98514507-98538670 (-)
AKR/J MGP_AKRJ_G0022293
protein coding gene Chr15:101520563-101547683 (-)
BALB/cJ MGP_BALBcJ_G0022321
protein coding gene Chr15:98622161-98649206 (-)
C3H/HeJ MGP_C3HHeJ_G0022091
protein coding gene Chr15:101602391-101630309 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022769
protein coding gene Chr15:106400159-106430548 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020294
protein coding gene Chr15:94265843-94290651 (-)
CAST/EiJ MGP_CASTEiJ_G0021616
protein coding gene Chr15:102451332-102474631 (-)
CBA/J MGP_CBAJ_G0022060
protein coding gene Chr15:110032922-110071344 (-)
DBA/2J MGP_DBA2J_G0022187
protein coding gene Chr15:97864834-97890208 (-)
FVB/NJ MGP_FVBNJ_G0022166
protein coding gene Chr15:96885316-96909780 (-)
LP/J MGP_LPJ_G0022258
protein coding gene Chr15:102705674-102734913 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022187
protein coding gene Chr15:113772739-113799269 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022783
protein coding gene Chr15:101522373-101551278 (-)
PWK/PhJ MGP_PWKPhJ_G0021355
protein coding gene Chr15:97992768-98021523 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021187
protein coding gene Chr15:101414646-101442245 (-)
WSB/EiJ MGP_WSBEiJ_G0021666
protein coding gene Chr15:102145554-102173294 (-)



Homology
more
  • Human Ortholog
    POU6F1, POU class 6 homeobox 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POU6F1, POU class 6 homeobox 1
  • Synonyms
    BRN5, MPOU, TCFB1
  • Links
    NCBI Gene ID: 5463
    neXtProt AC: NX_Q14863
    UniProt: Q14863

  • Chr Location
    12q13.13; chr12:51186936-51218062 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000009739 Ensembl Gene Model | MGI Sequence Detail 24667 C57BL/6J ±  kb
transcript ENSMUST00000073837 Ensembl | MGI Sequence Detail 4953 Not Applicable  
polypeptide ENSMUSP00000073504 Ensembl | MGI Sequence Detail 576 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    Genomic 3
    cDNA 71
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-23769, MGI:1914205, MGI:2146292
References
more
  • Summaries
    All 68
    Developmental Gene Expression 12
    Diseases 1
    Gene Ontology 6
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:333394 Wu D, et al., RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation. Cell Rep. 2023 Jan 30;42(2):112047

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory