Serpina3c
Gene Detail

Symbol Name ID

Serpina3c serine (or cysteine) peptidase inhibitor, clade A, member 3C MGI:102848

Synonyms

1A1, alpha-1 antiproteinase, Kalbp, Klkbp

Feature Type

protein coding gene

Genetic Map

Chromosome 12

53.46 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr12:104146382-104153870 bp, - strand From VEGA annotation of GRCm38   7489 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40659  Vertebrate Homology Class
3 mouse; 1 rat

Protein SuperFamily: serpin
Gene Tree: Serpina3c

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component	extracellular region
Function	peptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (1)    Images (3)
Theiler Stages: 23

Assay Type	Results
RNA in situ	3

cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(9) Genomic(2) cDNA(7)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000027583 (Evidence)
Ensembl Gene Model	ENSMUSG00000066361 (Evidence)
Entrez Gene	16625 (Evidence)
UniGene	422814
DFCI	TC1589989
DoTS	DT.91491101
NIA Mouse Gene Index	U034304
Consensus CDS Project	CCDS26148.1
International Mouse Knockout Project Status	Serpina3c

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027583	VEGA Gene Model | MGI Sequence Detail	7489	C57BL/6J
transcript	OTTMUST00000068294	VEGA | MGI Sequence Detail	2213	Not Applicable
polypeptide	OTTMUSP00000034490	VEGA | MGI Sequence Detail	417	Not Applicable

All sequences(17) RefSeq(2) UniProt(2)

Polymorphisms

SNPs within 2kb(194 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family
Protein Ontology	PR:000015935	serine protease inhibitor A3C

References

(Earliest) J:1851 Chai KX, et al., Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene. Biochim Biophys Acta. 1991 Dec 2;1129(1):127-30
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Other accession IDs

MGD-MRK-11551, MGD-MRK-23681