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Serpina3c
Gene Detail
Symbol

Name
ID
Serpina3c
serine (or cysteine) peptidase inhibitor, clade A, member 3C
MGI:102848
Synonyms
1A1, alpha-1 antiproteinase, Kalbp, Klkbp
Feature Type
protein coding gene
Genetic Map
Chromosome 12
53.46 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:104146382-104153870 bp, - strand
From VEGA annotation of GRCm38

  7489 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:111129  Vertebrate Homology Class
1 human; 4 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 6 cattle; 1 dog

HCOP human homology predictions: SERPINA3
Protein SuperFamily: serpin
Gene Tree: Serpina3c

Human
homologs
SERPINA3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 12
neXtProt AC: NX_P01011

Human Synonyms: AACT, ACT, GIG24, GIG25

Human Chr (Location): 14q32.1; chr14:94612377-94624053 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpina3c interacts with 129 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (1)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
cDNA source data(7)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) Genomic(2) cDNA(7)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000027583 (Evidence)
Ensembl Gene Model ENSMUSG00000066361 (Evidence)
Entrez Gene 16625 (Evidence)
UniGene 422814
DFCI TC1589989
DoTS DT.91491101
NIA Mouse Gene Index U034304
Consensus CDS Project CCDS26148.1
International Mouse Phenotyping Consortium Status Serpina3c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027583 VEGA Gene Model | MGI Sequence Detail 7489 C57BL/6J ±  kb
transcript OTTMUST00000068294 VEGA | MGI Sequence Detail 2213 Not Applicable 
polypeptide OTTMUSP00000034490 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(194 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000015935 serine protease inhibitor A3C
References
(Earliest) J:1851 Chai KX, et al., Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene. Biochim Biophys Acta. 1991 Dec 2;1129(1):127-30
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGD-MRK-11551, MGD-MRK-23681

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory