About   Help   FAQ
Pmp2 Gene Detail
Summary
  • Symbol
    Pmp2
  • Name
    peripheral myelin protein 2
  • Synonyms
    P2
  • Feature Type
    protein coding gene
  • IDs
    MGI:102667
    NCBI Gene: 18857
  • Gene Overview
    MyGene.info: PMP2
Location & Maps
more
  • Sequence Map
    Chr3:10179851-10183929 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4079 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PMP2, peripheral myelin protein 2
  • Vertebrate Orthologs
    12
  • Human Ortholog
    PMP2, peripheral myelin protein 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FABP8, M-FABP, MP2, P2
  • Links
    NCBI Gene ID: 5375
    neXtProt AC: NX_P02689

  • Chr Location
    8q21.3-q22.1; chr8:81440326-81447484 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051460 VEGA Gene Model | MGI Sequence Detail 4079 C57BL/6J ±  kb
transcript OTTMUST00000130036 VEGA | MGI Sequence Detail 1408 Not Applicable  
polypeptide OTTMUSP00000069769 VEGA | MGI Sequence Detail 132 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    56 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 2
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-19568
References
more
  • Summaries
    All 23
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:11254 Narayanan V, et al., Structure of the mouse myelin P2 protein gene. J Neurochem. 1991 Jul;57(1):75-80
  • Latest
    J:211344 Zenker J, et al., A role of peripheral myelin protein 2 in lipid homeostasis of myelinating schwann cells. Glia. 2014 Sep;62(9):1502-12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory