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Pmp2
Gene Detail
 Symbol
Name
ID
Pmp2
peripheral myelin protein 2
MGI:102667
STS D3Mit130
Synonyms P2
Feature Type protein coding gene
Genetic Map
Chromosome 3
2.54 cM
Detailed Genetic Map ± 1 cM

Sequence Map
Chr3:10179851-10183885 bp, - strand
From NCBI annotation of GRCm38

  4035 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20589  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 4 zebrafish

Protein SuperFamily: lipid binding protein, FABP type
Gene Tree: Pmp2

Human
homologs
Human Homolog PMP2, peripheral myelin protein 2
NCBI Gene ID 5375
neXtProt AC  NX_P02689
Human Synonyms  FABP8, M-FABP, MP2, P2
Human Chr (Location)  8q21.3-q22.1; chr8:81440326-81447484 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pmp2 interacts with 125 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process membrane organization, transport
Component cytoplasm, extracellular vesicular exosome
Function cholesterol binding, fatty acid binding, ...
External Resources: FuncBase
Expression
cDNA source data(3)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(6) Genomic(2) cDNA(4)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000052468 (Evidence)
Entrez Gene18857 (Evidence)
UniGene371777
DFCITC1591192
DoTSDT.60100875, DT.97380035
NIA Mouse Gene IndexU095839
Consensus CDS ProjectCCDS17236.1
International Mouse Knockout Project StatusPmp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 18857 NCBI Gene Model | MGI Sequence Detail 4035 C57BL/6J ±  kb
transcript NM_001030305 RefSeq | MGI Sequence Detail 1364 C57BL/6 
polypeptide P24526 UniProt | EBI | MGI Sequence Detail 132 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(74 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012674 Calycin
InterPro IPR011038 Calycin-like
InterPro IPR000463 Cytosolic fatty-acid binding
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology PR:000012909 myelin P2 protein
Graphical View of Protein Domain Structure
References (Earliest) J:11254 Narayanan V, et al., Structure of the mouse myelin P2 protein gene. J Neurochem. 1991 Jul;57(1):75-80
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)
Other
accession IDs
MGD-MRK-19568

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory