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Pmp2
Gene Detail
Symbol

Name
ID
Pmp2
peripheral myelin protein 2
MGI:102667
STS
Synonyms
P2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
2.54 cM
Detailed Genetic Map ± 1 cM

Sequence Map
Chr3:10179851-10183929 bp, - strand
From VEGA annotation of GRCm38

  4079 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20589  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 4 zebrafish

HCOP human homology predictions: PMP2
Protein SuperFamily: lipid binding protein, FABP type
Gene Tree: Pmp2

Human
homologs
PMP2, peripheral myelin protein 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5375
neXtProt AC: NX_P02689

Human Synonyms: FABP8, M-FABP, MP2, P2

Human Chr (Location): 8q21.3-q22.1; chr8:81440326-81447484 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pmp2 interacts with 125 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process membrane organization, transport
Component cytoplasm, extracellular exosome
Function cholesterol binding, fatty acid binding, ...
External Resources: FuncBase
Expression
cDNA source data(3)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase pmp2    NEW 
Molecular
reagents
All nucleic(6) Genomic(2) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000051460 (Evidence)
Ensembl Gene Model ENSMUSG00000052468 (Evidence)
Entrez Gene 18857 (Evidence)
UniGene 371777
DFCI TC1591192
DoTS DT.97380035, DT.60100875
NIA Mouse Gene Index U095839
Consensus CDS Project CCDS17236.1
International Mouse Phenotyping Consortium Status Pmp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051460 VEGA Gene Model | MGI Sequence Detail 4079 C57BL/6J ±  kb
transcript OTTMUST00000130036 VEGA | MGI Sequence Detail 1408 Not Applicable 
polypeptide OTTMUSP00000069769 VEGA | MGI Sequence Detail 132 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(74 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012674 Calycin
InterPro IPR011038 Calycin-like
InterPro IPR000463 Cytosolic fatty-acid binding
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology PR:000012909 myelin P2 protein
References
(Earliest) J:11254 Narayanan V, et al., Structure of the mouse myelin P2 protein gene. J Neurochem. 1991 Jul;57(1):75-80
(Latest) J:211344 Zenker J, et al., A role of peripheral myelin protein 2 in lipid homeostasis of myelinating schwann cells. Glia. 2014 Sep;62(9):1502-12
All references(26)
Other
accession IDs
MGD-MRK-19568

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory