mt-Nd2
Gene Detail

Symbol Name ID

mt-Nd2 mitochondrially encoded NADH dehydrogenase 2 MGI:102500

Synonyms

URF2

Feature Type

protein coding gene

Genetic Map

Chromosome MT
Syntenic

Sequence Map

ChrMT:3914-4951 bp, + strand From NCBI annotation of GRCm38   1038 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5019  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: mt-Nd2

Human homologs

Human Homolog		ND2, MTND2
NCBI Gene ID		4536
neXtProt AC		NX_P03891
Human Synonyms		MTND2
Human Chr (Location)		MT
Disease Associations		(1) Diseases Associated with Human ND2

Alleles and phenotypes

All alleles(5) : Gene trapped(4) Spontaneous(1)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	electron transport chain, oxidation-reduction process, ...
Component	integral to membrane, membrane, ...
Function	ionotropic glutamate receptor binding, NADH dehydrogenase (ubiquinone) activity, ...

Expression

Literature Summary: (1 records)
Data Summary: Results (9)    Tissues (9)    Images (1)
Theiler Stages: 2, 3, 4, 5, 28

Assay Type	Results
RT-PCR	9

cDNA source data(16)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(69) cDNA(16) Primer pair(1) Other(52)

Other database links

Ensembl Gene Model	ENSMUSG00000064345 (Evidence)
Entrez Gene	17717
EC	1.6.5.3
International Mouse Knockout Project Status	mt-Nd2

Sequences

Length	Strain/Species
genomic	17717	NCBI Gene Model | MGI Sequence Detail	1038	C57BL/6J
transcript	AK167184	GenBank | EMBL | DDBJ | MGI Sequence Detail	1259	C57BL/6J
polypeptide	NP_904329	RefSeq | MGI Sequence Detail	345	C57BL/6J

All sequences(58) RefSeq(1) UniProt(1)

Protein-related information

Resource	ID	Description
InterPro	IPR010933	NADH dehydrogenase subunit 2, C-terminal
InterPro	IPR003917	NADH:ubiquinone oxidoreductase, chain 2
InterPro	IPR001750	NADH:ubiquinone/plastoquinone oxidoreductase

References

(Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:170153 Chen J, et al., mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic beta-cell. Diabetes. 2011 Jan;60(1):355-9
All references(30)

Other accession IDs

MGD-MRK-19337, MGI:2139164, MGI:2139169, MGI:2139170, MGI:2139183, MGI:2139189, MGI:2139190, MGI:2139191, MGI:2139224