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mt-Nd2
Gene Detail
 Symbol
Name
ID
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
MGI:102500
Synonyms URF2
Feature Type protein coding gene
Genetic Map
Chromosome MT
Syntenic
Sequence Map
ChrMT:3914-4951 bp, + strand
From NCBI annotation of GRCm38

  1038 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
HomoloGene:5019  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: mt-Nd2

Human
homologs
Human Homolog ND2, MTND2
NCBI Gene ID 4536
neXtProt AC  NX_P03891
Human Synonyms  MTND2
Human Chr (Location)  MT
Disease Associations  (1) Diseases Associated with Human ND2
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Spontaneous(1)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process oxidation-reduction process, reactive oxygen species metabolic process, ...
Component integral component of membrane, membrane, ...
Function ionotropic glutamate receptor binding, NADH dehydrogenase (ubiquinone) activity, ...
Expression
Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (5)    Images (1)
Theiler Stages: 2, 3, 4, 28
Assay TypeResults
RT-PCR 5
cDNA source data(16)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(69) cDNA(16) Primer pair(1) Other(52)
Other database
links
Ensembl Gene ModelENSMUSG00000064345 (Evidence)
Entrez Gene17717
EC1.6.5.3
International Mouse Knockout Project Statusmt-Nd2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 17717 NCBI Gene Model | MGI Sequence Detail 1038 C57BL/6J ±  kb
transcript AK167184 GenBank | EMBL | DDBJ | MGI Sequence Detail 1259 C57BL/6J 
polypeptide NP_904329 RefSeq | MGI Sequence Detail 345 C57BL/6J 

For the selected sequences
All sequences(58) RefSeq(1) UniProt(1)
Polymorphisms SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010933 NADH dehydrogenase subunit 2, C-terminal
InterPro IPR003917 NADH:ubiquinone oxidoreductase, chain 2
InterPro IPR001750 NADH:ubiquinone/plastoquinone oxidoreductase
References (Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:170153 Chen J, et al., mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic beta-cell. Diabetes. 2011 Jan;60(1):355-9
All references(30)
Other
accession IDs
MGD-MRK-19337, MGI:2139164, MGI:2139169, MGI:2139170, MGI:2139183, MGI:2139189, MGI:2139190, MGI:2139191, MGI:2139224

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory