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mt-Nd4
Gene Detail
 Symbol
Name
ID
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
MGI:102498
Synonyms URF4
Feature Type protein coding gene
Genetic Map
Chromosome MT
Syntenic
Sequence Map
ChrMT:10167-11544 bp, + strand
From NCBI annotation of GRCm38

  1378 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
HomoloGene:38240  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: NADH dehydrogenase (ubiquinone) chain 4
Gene Tree: mt-Nd4

Human
homologs
Human Homolog ND4, NADH dehydrogenase, subunit 4 (complex I)
NCBI Gene ID 4538
neXtProt AC  NX_P03905
Human Synonyms  MTND4
Human Chr (Location)  MT
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process aging, ATP synthesis coupled electron transport, ...
Component integral component of membrane, membrane, ...
Function NADH dehydrogenase (ubiquinone) activity, oxidoreductase activity
External Resources: FuncBase
Expression
cDNA source data(14)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(66) cDNA(14) Other(52)
Other database
links
Ensembl Gene ModelENSMUSG00000064363 (Evidence)
Entrez Gene17719
DFCITC1683147
EC1.6.5.3
International Mouse Knockout Project Statusmt-Nd4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 17719 NCBI Gene Model | MGI Sequence Detail 1378 C57BL/6J ±  kb
transcript BC050862 GenBank | EMBL | DDBJ | MGI Sequence Detail 3663 Not Specified 
polypeptide P03911 UniProt | EBI | MGI Sequence Detail 459 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(1) UniProt(4)
Polymorphisms SNPs within 2kb(62 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010227 NADH-quinone oxidoreductase, chain M/4
InterPro IPR003918 NADH:ubiquinone oxidoreductase
InterPro IPR000260 NADH:ubiquinone oxidoreductase, chain 4, N-terminal
InterPro IPR001750 NADH:ubiquinone/plastoquinone oxidoreductase
Graphical View of Protein Domain Structure
References (Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:162575 Perales-Clemente E, et al., Five entry points of the mitochondrially encoded subunits in mammalian complex I assembly. Mol Cell Biol. 2010 Jun;30(12):3038-47
All references(28)
Other
accession IDs
MGD-MRK-19335, MGI:2138392, MGI:2138399, MGI:2138421, MGI:2138441

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory