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Usp15 Gene Detail
Summary
  • Symbol
    Usp15
  • Name
    ubiquitin specific peptidase 15
  • Synonyms
    4921514G19Rik, E430033I05Rik, Gcap18, mKIAA0529
  • Feature Type
    protein coding gene
  • IDs
    MGI:101857
    NCBI Gene: 14479
  • Gene Overview
    MyGene.info: USP15
Location & Maps
more
  • Sequence Map
    Chr10:123113244-123196935 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      83692 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 72.31 cM, cytoband D3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    USP15, ubiquitin specific peptidase 15
  • Vertebrate Orthologs
    9
  • Human Ortholog
    USP15, ubiquitin specific peptidase 15
    Orthology source: HGNC, HomoloGene
  • Synonyms
    UNPH-2, UNPH4
  • Links
    NCBI Gene ID: 9958
    neXtProt AC: NX_Q9Y4E8

  • Chr Location
    12q14; chr12:62260340-62409721 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    21
  • Chemically induced (ENU)
    1
  • Gene trapped
    18
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020124 Ensembl Gene Model | MGI Sequence Detail 83692 C57BL/6J ±  kb
transcript ENSMUST00000020334 Ensembl | MGI Sequence Detail 3227 Not Applicable  
polypeptide ENSMUSP00000020334 Ensembl | MGI Sequence Detail 981 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    756 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000017151 ubiquitin carboxyl-terminal hydrolase 15
  • EC
  • InterPro Domains
    IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
    IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta
    IPR029346 Ubiquitin carboxyl-terminal hydrolase, C-terminal
    IPR028135 Ubiquitin-like domain, USP-type
    IPR029071 Ubiquitin-related domain
    IPR018200 Ubiquitin specific protease, conserved site
    IPR028889 Ubiquitin specific protease domain
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-18681, MGI:1918171, MGI:2143588
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:19885 Kambouris M, et al., Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library. Brain Res Mol Brain Res. 1994 Sep;25(3-4):183-91
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory