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Phenotype Images associated with this Gene
Symbol
Name
ID
Ldlr
low density lipoprotein receptor
MGI:96765


9 phenotype image(s) for Ldlr alleles
Showing image(s) 1 to 9

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Click on allele symbol for full phenotype details.

Caption: Atherosclerosis lesion area is increased in Ldlrtm1Her/Ldlrtm1Her Nr1h3tm1.1Djm/Nr1h3tm1.1Djm Tg(Alb-cre)21Mgn/0 mice and TO901317 treatment reduces these lesions (details)
Represented Alleles:
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Nr1h3tm1.1Djm, nuclear receptor subfamily 1, group H, member 3; targeted mutation 1.1, David J Mangelsdorf
Tg(Alb-cre)21Mgn, transgene insertion 21, Mark A Magnuson
Copyright: This image is from Zhang Y, J Clin Invest 2012 May 1;122(5):1688-99 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184536
Caption: Increase in macrophage content in Ldlrtm1Her/Ldlrtm1Her Nr1h3tm1.1Djm/Nr1h3tm1.1Djm Tg(Alb-cre)21Mgn/0 aortic root (details)
Represented Alleles:
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Nr1h3tm1.1Djm, nuclear receptor subfamily 1, group H, member 3; targeted mutation 1.1, David J Mangelsdorf
Tg(Alb-cre)21Mgn, transgene insertion 21, Mark A Magnuson
Copyright: This image is from Zhang Y, J Clin Invest 2012 May 1;122(5):1688-99 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184536
Caption: Adiposity in Ldlrtm1Her/Ldlrtm1Her and Scd1ab-2J/Scd1ab-2J Ldlrtm1Her/Ldlrtm1Her mice (details)
Represented Alleles:
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Scd1ab-2J, stearoyl-Coenzyme A desaturase 1; asebia 2 Jackson
Copyright: This image is from MacDonald ML, J Lipid Res 2008 Jan;49(1):217-29 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:130278
Caption: Hepatic lipids in Ldlrtm1Her/Ldlrtm1Her and Scd1ab-2J/Scd1ab-2J Ldlrtm1Her/Ldlrtm1Her mice (details)
Represented Alleles:
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Scd1ab-2J, stearoyl-Coenzyme A desaturase 1; asebia 2 Jackson
Copyright: This image is from MacDonald ML, J Lipid Res 2008 Jan;49(1):217-29 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text is from JLR. J:130278
Caption: Phenotype of aortic arch atherosclerotic lesions in Tbx21tm1Glm/Tbx21tm1Glm Ldlrtm1Her/Ldlrtm1Her and Ldlrtm1Her/Ldlrtm1Her mice (details)
Represented Alleles:
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Tbx21tm1Glm, T-box 21; targeted mutation 1, Laurie H Glimcher
Copyright: This image is from Buono C, Proc Natl Acad Sci U S A 2005 Feb 1;102(5):1596-601. Copyright 2005 National Academy of Sciences, U.S.A. J:96110
Caption: Cutaneous xanthomatosis and alopecia in Soat1tm1Ishi/Soat1tm1Ishi Apoetm1Unc/Apoetm1Unc and Soat1tm1Ishi/Soat1tm1Ishi Ldlrtm1Her/Ldlrtm1Her mice (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Soat1tm1Ishi, sterol O-acyltransferase 1; targeted mutation 1, Shun Ishibashi
Copyright: This image is from Yagyu H, J Biol Chem 2000 Jul 14;275(28):21324-30 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:63468
Caption: Histopathology of cutaneous lesions developed in Soat1tm1Ishi/Soat1tm1Ishi Apoetm1Unc/Apoetm1Unc and Soat1tm1Ishi/Soat1tm1Ishi Ldlrtm1Her/Ldlrtm1Her mice fed high fat diets (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Soat1tm1Ishi, sterol O-acyltransferase 1; targeted mutation 1, Shun Ishibashi
Copyright: This image is from Yagyu H, J Biol Chem 2000 Jul 14;275(28):21324-30 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:63468
Caption: Soat1tm1Far/Soat1tm1Far Ldlrtm1Her/Ldlrtm1Her mice fed an atherogenic diet for 2 months display severe xanthomatosis (details)
Represented Alleles:
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Soat1tm1Far, sterol O-acyltransferase 1; targeted mutation 1, Bob Farese
Copyright: This image is from Accad M, J Clin Invest 2000 Mar;105(6):711-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:61147
Caption: Neutral lipid-poor atherosclerotic lesions in Apoetm1Unc/Apoetm1Unc Soat1tm1Far/Soat1tm1Far and Soat1tm1Far/Soat1tm1Far Ldlrtm1Her/Ldlrtm1Her mice (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Soat1tm1Far, sterol O-acyltransferase 1; targeted mutation 1, Bob Farese
Copyright: This image is from Accad M, J Clin Invest 2000 Mar;105(6):711-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:61147

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory