Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Apoe
apolipoprotein E
MGI:88057

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Click on allele symbol for full phenotype details.

	Caption: Assessment of atherosclerosis initiation and progression in tamoxifen-treated, high-fat diet fed Apoe^tm1Unc/Apoe^tm1Unc Tg(Cdh5-cre/ERT2)1Rha/0 Nck1^tm1Paw/Nck1^tm1Paw Nck2^tm3Paw/Nck2^tm3Paw mice. (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Nck1^tm1Paw, non-catalytic region of tyrosine kinase adaptor protein 1; targeted mutation 1, Tony Pawson Nck2^tm3Paw, non-catalytic region of tyrosine kinase adaptor protein 2; targeted mutation 3, Tony Pawson Tg(Cdh5-cre/ERT2)1Rha, transgene insertion 1, Ralf H Adams Copyright: This image is from the Laboratory of Dr. Gonzalo M Rivera at Texas A&M University and is displayed with the permission of the author. J:327349
	Caption: Morphometric analysis of aortic root lesions in tamoxifen-treated, high-fat diet fed Apoe^tm1Unc/Apoe^tm1Unc Tg(Cdh5-cre/ERT2)1Rha/0 Nck1^tm1Paw/Nck1^tm1Paw Nck2^tm3Paw/Nck2^tm3Paw mice. (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Nck1^tm1Paw, non-catalytic region of tyrosine kinase adaptor protein 1; targeted mutation 1, Tony Pawson Nck2^tm3Paw, non-catalytic region of tyrosine kinase adaptor protein 2; targeted mutation 3, Tony Pawson Tg(Cdh5-cre/ERT2)1Rha, transgene insertion 1, Ralf H Adams Copyright: This image is from the Laboratory of Dr. Gonzalo M Rivera at Texas A&M University and is displayed with the permission of the author. J:327349
	Caption: Determination of ICAM-1 in aortic roots of tamoxifen treated, high-fat diet fed Apoe^tm1Unc/Apoe^tm1Unc Tg(Cdh5-cre/ERT2)1Rha/0 Nck1^tm1Paw/Nck1^tm1Paw Nck2^tm3Paw/Nck2^tm3Paw mice. (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Nck1^tm1Paw, non-catalytic region of tyrosine kinase adaptor protein 1; targeted mutation 1, Tony Pawson Nck2^tm3Paw, non-catalytic region of tyrosine kinase adaptor protein 2; targeted mutation 3, Tony Pawson Tg(Cdh5-cre/ERT2)1Rha, transgene insertion 1, Ralf H Adams Copyright: This image is from the Laboratory of Dr. Gonzalo M Rivera at Texas A&M University and is displayed with the permission of the author. J:327349
	Caption: Reduced inflammation in aortic roots obtained from tamoxifen-treated, high-fat diet fed Apoe^tm1Unc/Apoe^tm1Unc Tg(Cdh5-cre/ERT2)1Rha/0 Nck1^tm1Paw/Nck1^tm1Paw Nck2^tm3Paw/Nck2^tm3Paw mice. (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Nck1^tm1Paw, non-catalytic region of tyrosine kinase adaptor protein 1; targeted mutation 1, Tony Pawson Nck2^tm3Paw, non-catalytic region of tyrosine kinase adaptor protein 2; targeted mutation 3, Tony Pawson Tg(Cdh5-cre/ERT2)1Rha, transgene insertion 1, Ralf H Adams Copyright: This image is from the Laboratory of Dr. Gonzalo M Rivera at Texas A&M University and is displayed with the permission of the author. J:327349
	Caption: Klf15^tm2Jain/Klf15^tm2Jain Tg(Tagln-cre)1Jjl/0 Apoe^tm1Unc/Apoe^tm1Unc aortas develop more atherosclerotic lesions after a high fat diet challenge (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Klf15^tm2Jain, Kruppel-like transcription factor 15; targeted mutation 2, Mukesh K Jain Tg(Tagln-cre)1Jjl, transgene insertion 1, John J Lepore Copyright: This image is from Lu Y, J Clin Invest 2013 Oct 1;123(10):4232-41 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203920
	Caption: Apoe^tm1Unc/Apoe^tm1Unc Scarb1^tm1Kri/Scarb1^tm1Kri mice develop occlusive, atherosclerotic coronary artery disease (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Scarb1^tm1Kri, scavenger receptor class B, member 1; targeted mutation 1, Monty Krieger Copyright: This image is from Tsukamoto K, Proc Natl Acad Sci U S A 2013 Oct 15;110(42):17023-8. Copyright 2013 National Academy of Sciences, U.S.A. J:201999
	Caption: Decreased aortic root atherosclerosis susceptibility in Apoe^tm1Unc/Apoe^tm1Unc Hsd11b1^tm1Lex/Hsd11b1^tm1Lex mice (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Hsd11b1^tm1Lex, hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Lexicon Genetics Copyright: This image is from Garcia RA, PLoS One 2013;8(2):e53192, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199430
	Caption: Lower levels of lipid droplets in Apoe^tm1Unc/Apoe^tm1Unc Hsd11b1^tm1Lex/Hsd11b1^tm1Lex macrophages (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Hsd11b1^tm1Lex, hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Lexicon Genetics Copyright: This image is from Garcia RA, PLoS One 2013;8(2):e53192, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199430
	Caption: Decreased susceptibility to atherosclerosis in Apoe^tm1Unc/Apoe^tm1Unc Dp(17Nfkbil1-Or2h1)1Cogr/0 mice (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Dp(17Nfkbil1-Or2h1)1Cogr, duplication, Chr 17, Cornelius Gross 1 Copyright: This image is from Ermakova O, Mamm Genome 2012 Aug;23(7-8):443-53 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:190754
	Caption: Morphology of aortic lesions in Apoe^tm1Unc/Apoe^tm1Unc and Apoe^tm1Unc/Apoe^tm1Unc Ttpa^tm1Far/Ttpa^tm1Far mice (details) Represented Alleles: Apoe^tm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina Ttpa^tm1Far, tocopherol (alpha) transfer protein; targeted mutation 1, Bob Farese Copyright: This image is from Terasawa Y, Proc Natl Acad Sci U S A 2000 Dec 5;97(25):13830-4. Copyright 2000 National Academy of Sciences, U.S.A. J:66419

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