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Phenotype Images associated with this Gene
Symbol
Name
ID
Apoe
apolipoprotein E
MGI:88057


13 phenotype image(s) for Apoe alleles
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Caption: Decreased aortic root atherosclerosis susceptibility in Apoetm1Unc/Apoetm1Unc Hsd11b1tm1Lex/Hsd11b1tm1Lex mice (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Hsd11b1tm1Lex, hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Lexicon Genetics
Copyright: This image is from Garcia RA, PLoS One 2013;8(2):e53192, an open-access article distributed under the terms of the Creative Commons Attribution License. J:199430
Caption: Lower levels of lipid droplets in Apoetm1Unc/Apoetm1Unc Hsd11b1tm1Lex/Hsd11b1tm1Lex macrophages (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Hsd11b1tm1Lex, hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Lexicon Genetics
Copyright: This image is from Garcia RA, PLoS One 2013;8(2):e53192, an open-access article distributed under the terms of the Creative Commons Attribution License. J:199430
Caption: Decreased susceptibility to atherosclerosis in Apoetm1Unc/Apoetm1Unc Dp(17Nfkbil1-Olfr91)1Cogr/0 mice (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Dp(17Nfkbil1-Olfr91)1Cogr, duplication, Chr 17, Cornelius Gross 1
Copyright: This image is from Ermakova O, Mamm Genome 2012 Aug;23(7-8):443-53 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:190754
Caption: Morphology of aortic lesions in Apoetm1Unc/Apoetm1Unc and Apoetm1Unc/Apoetm1Unc Ttpatm1Far/Ttpatm1Far mice (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Ttpatm1Far, tocopherol (alpha) transfer protein; targeted mutation 1, Bob Farese
Copyright: This image is from Terasawa Y, Proc Natl Acad Sci U S A 2000 Dec 5;97(25):13830-4. Copyright 2000 National Academy of Sciences, U.S.A. J:66419
Caption: Cutaneous xanthomatosis and alopecia in Soat1tm1Ishi/Soat1tm1Ishi Apoetm1Unc/Apoetm1Unc and Soat1tm1Ishi/Soat1tm1Ishi Ldlrtm1Her/Ldlrtm1Her mice (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Soat1tm1Ishi, sterol O-acyltransferase 1; targeted mutation 1, Shun Ishibashi
Copyright: This image is from Yagyu H, J Biol Chem 2000 Jul 14;275(28):21324-30 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:63468
Caption: Histopathology of cutaneous lesions developed in Soat1tm1Ishi/Soat1tm1Ishi Apoetm1Unc/Apoetm1Unc and Soat1tm1Ishi/Soat1tm1Ishi Ldlrtm1Her/Ldlrtm1Her mice fed high fat diets (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Soat1tm1Ishi, sterol O-acyltransferase 1; targeted mutation 1, Shun Ishibashi
Copyright: This image is from Yagyu H, J Biol Chem 2000 Jul 14;275(28):21324-30 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:63468
Caption: Apoetm1Unc/Apoetm1Unc Soat1tm1Far/Soat1tm1Far mice display severe xanthomatosis (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Soat1tm1Far, sterol O-acyltransferase 1; targeted mutation 1, Bob Farese
Copyright: This image is from Accad M, J Clin Invest 2000 Mar;105(6):711-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:61147
Caption: Neutral lipid-poor atherosclerotic lesions in Apoetm1Unc/Apoetm1Unc Soat1tm1Far/Soat1tm1Far and Soat1tm1Far/Soat1tm1Far Ldlrtm1Her/Ldlrtm1Her mice (details)
Represented Alleles:
Apoetm1Unc, apolipoprotein E; targeted mutation 1, University of North Carolina
Ldlrtm1Her, low density lipoprotein receptor; targeted mutation 1, Joachim Herz
Soat1tm1Far, sterol O-acyltransferase 1; targeted mutation 1, Bob Farese
Copyright: This image is from Accad M, J Clin Invest 2000 Mar;105(6):711-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:61147
Caption: Xanthoma of Apoeshl/Apoeshl mice (details)
Represented Alleles:
Apoeshl, apolipoprotein E; spontaneous hyperlipidemia
Copyright: This image is from Matsushima Y, Mamm Genome 1999 Apr;10(4):352-7 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:54051
Caption: Signs of atherosclerosis in Apoeshl/Apoeshl mice (details)
Represented Alleles:
Apoeshl, apolipoprotein E; spontaneous hyperlipidemia
Copyright: This image is from Matsushima Y, Mamm Genome 1999 Apr;10(4):352-7 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:54051

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory