IL10 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	IL10	HGNC:5962 (HGNC) 3586 (Entrez Gene) 124092 (OMIM) IL10 (Alliance of Genome Resources)	Chr1 q32.1	Chr1:206767602-206774541 (-) GRCh38	acute pancreatitis aggressive periodontitis Alzheimer's disease aphthous stomatitis arteriosclerosis asthma autoimmune thrombocytopenic purpura Behcet's disease central nervous system lymphoma choroid disease chronic myeloid leukemia colon cancer common cold coronary artery disease Crohn's disease diabetic retinopathy factor VIII deficiency gallbladder carcinoma glucosephosphate dehydrogenase deficiency graft-versus-host disease granulomatosis with polyangiitis Graves' disease Graves ophthalmopathy hepatitis B hepatitis C hepatocellular carcinoma high grade glioma human immunodeficiency virus infectious disease inflammatory bowel disease liver carcinoma liver cirrhosis lymphoplasmacytic lymphoma major depressive disorder metabolic dysfunction-associated steatohepatitis multiple myeloma myocardial infarction oral squamous cell carcinoma otitis media pancreatic cancer panuveitis psoriasis retinal artery occlusion rheumatoid arthritis schizophrenia Sjogren's syndrome skin disease stomach cancer systemic lupus erythematosus thrombocytopenia toxic shock syndrome trachoma type 2 diabetes mellitus uveitis	P22301 (UniProt \| EBI) NM_001382624 (RefSeq)
mouse	Il10	MGI:96537 (MGI) 16153 (Entrez Gene) Gene Tree Il10 (Alliance of Genome Resources)	Chr1 56.89 cM	Chr1:130947582-130952711 (+) GRCm39	inflammatory bowel disease	ENSMUSG00000016529 (Ensembl Gene Model) ENSMUSP00000016673 (Ensembl) ENSMUST00000016673 (Ensembl)
rat	Il10	RGD:2886 (Rat Genome Database) 25325 (Entrez Gene) Il10 (Alliance of Genome Resources)	Chr13 q13			P29456 (UniProt \| EBI) NM_012854 (RefSeq)
zebrafish	il10	ZDB-GENE-051111-1 (Zebrafish Model Organism Database) 553957 (Entrez Gene) il10 (Alliance of Genome Resources)	Chr11			NP_001018621 (RefSeq) NM_001020785 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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