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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
37351

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACE HGNC:2707 (HGNC)
1636 (Entrez Gene)
106180 (OMIM)
Chr17 q23.3 Chr17:63477061-63498380 (+)
GRCh38
Alzheimer Disease; AD
Angiotensin I-Converting Enzyme; ACE
Hemorrhage, Intracerebral, Susceptibility To; ICH
Microvascular Complications of Diabetes, Susceptibility to, 3; MVCD3
Renal Tubular Dysgenesis; RTD
P12821 (UniProt | EBI)
NM_000789 (RefSeq)
mouse Ace MGI:87874 (MGI)
11421 (Entrez Gene)
Gene Tree
VISTA-Point
Chr11 68.84 cM Chr11:105967945-105989964 (+)
GRCm38
OTTMUSG00000003113 (VEGA)
OTTMUSP00000003021 (VEGA)
OTTMUST00000006415 (VEGA)
rat Ace 24310 (Entrez Gene)
Chr10 q32.1 P47820 (UniProt | EBI)
NM_012544 (RefSeq)
chimpanzee ACE 449567 (Entrez Gene)
Chr17 Q9GLN7 (UniProt | EBI)
NM_001008995 (RefSeq)
rhesus macaque LOC100428661 100428661 (Entrez Gene)
Chr16 XP_002800616 (RefSeq)
cattle ACE 509484 (Entrez Gene)
Chr19 NP_001193597 (RefSeq)
NM_001206668 (RefSeq)
dog LOC610668 610668 (Entrez Gene)
Chr9 XP_003639297 (RefSeq)
chicken ACE 419953 (Entrez Gene)
Chr27 Q10751 (UniProt | EBI)
NM_001167732 (RefSeq)
western clawed frog ace 100144634 (Entrez Gene)
ChrUN NP_001116882 (RefSeq)
NM_001123410 (RefSeq)
zebrafish ace 565980 (Entrez Gene)
Chr12 XP_694336 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory