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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACE HGNC:2707 (HGNC)
1636 (Entrez Gene)
106180 (OMIM)
ACE (Alliance of Genome Resources)
Chr17 q23.3 Chr17:63477061-63498380 (+)
GRCh38
allergic disease
anemia
ankylosing spondylitis
aspiration pneumonia
asthma
atrial fibrillation
Behcet's disease
breast cancer
cerebral infarction
chronic obstructive pulmonary disease
coronary artery disease
Coronavirus infectious disease
COVID-19
diabetic retinopathy
diastolic heart failure
end stage renal disease
Fabry disease
familial mediterranean fever
gallbladder adenocarcinoma
heart valve disease
Henoch-Schoenlein purpura
hepatitis A
hepatocellular carcinoma
hypertension
IgA glomerulonephritis
leukemia
liver cirrhosis
lung cancer
mitral valve disease
mitral valve prolapse
multiple myeloma
myocardial infarction
nephritis
non-arteritic anterior ischemic optic neuropathy
obstructive sleep apnea
pneumonia
polycythemia
pre-eclampsia
proteinuria
sarcoidosis
stomach cancer
subacute sclerosing panencephalitis
toxic shock syndrome
type 1 diabetes mellitus
type 2 diabetes mellitus
P12821 (UniProt | EBI)
NM_001382702 (RefSeq)
mouse Ace MGI:87874 (MGI)
11421 (Entrez Gene)
Gene Tree
Ace (Alliance of Genome Resources)
Chr11 68.84 cM Chr11:105858774-105880790 (+)
GRCm39
11421 (NCBI Gene Model)
P09470 (UniProt | EBI)
NM_001281819 (RefSeq)
rat Ace RGD:2493 (Rat Genome Database)
24310 (Entrez Gene)
Ace (Alliance of Genome Resources)
Chr10 q32.1 P47820 (UniProt | EBI)
NM_012544 (RefSeq)
zebrafish ace ZDB-GENE-030131-1826 (Zebrafish Model Organism Database)
565980 (Entrez Gene)
ace (Alliance of Genome Resources)
Chr12 XP_694336 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory