Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPM2
  • Mouse genes Tpm2
  • Rat genes Tpm2
  • Zfish genes tpm2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	TPM2	IDA		Human	PMID:17194691
Molecular Function	GO:0051015	actin filament binding	Tpm2	IDA		Rat	PMID:22812662|RGD:12910998
Molecular Function	GO:0051015	actin filament binding	Tpm2	IDA		Rat	PMID:7568216|RGD:12911000
Molecular Function	GO:0042802	identical protein binding	Tpm2	IDA		Rat	PMID:22812662|RGD:12910998
Molecular Function	GO:0042802	identical protein binding	Tpm2	IDA		Rat	PMID:7568216|RGD:12911000
Molecular Function	GO:0005515	protein binding	Tpm2	IPI	PR:Q8BMZ5	Mouse	PMID:11591653
Molecular Function	GO:0046982	protein heterodimerization activity	Tpm2	IDA		Rat	PMID:22812662|RGD:12910998
Molecular Function	GO:0046982	protein heterodimerization activity	Tpm2	IDA		Rat	PMID:7568216|RGD:12911000
Molecular Function	GO:0042803	protein homodimerization activity	Tpm2	IDA		Rat	PMID:22812662|RGD:12910998
Molecular Function	GO:0042803	protein homodimerization activity	Tpm2	IDA		Rat	PMID:7568216|RGD:12911000
Cellular Component	GO:0015629	actin cytoskeleton	Tpm2	IDA		Rat	PMID:7568216|RGD:12911000
Cellular Component	GO:0005865	striated muscle thin filament	tpm2	IDA		Zfish	PMID:23413262
Biological Process	GO:0043462	regulation of ATP-dependent activity	TPM2	IDA		Human	PMID:17194691

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern