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Tpm2
Gene Detail
Symbol

Name
ID
Tpm2
tropomyosin 2, beta
MGI:98810
Synonyms
Tpm-2, Trop-2
Feature Type
protein coding gene
Genetic Map
Chromosome 4
23.05 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:43514711-43523765 bp, - strand
From VEGA annotation of GRCm38

  9055 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134309  Vertebrate Homology Class
1 mouse; 1 rat; 1 dog; 1 western clawed frog

Gene Tree: Tpm2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tpm2 interacts with 214 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process muscle contraction
Component cytoplasm, cytoskeleton, ...
Function actin binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (86)    Tissues (75)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 79
Western blot 7
cDNA source data(221)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(224) Genomic(1) cDNA(223)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000006959 (Evidence)
Ensembl Gene ModelENSMUSG00000028464 (Evidence)
Entrez Gene22004 (Evidence)
UniGene646
DFCITC1574818, TC1581419, TC1591984, TC1705464
DoTSDT.101285596, DT.94358880, DT.97383083
NIA Mouse Gene IndexU024989
Consensus CDS ProjectCCDS18100.1, CCDS71374.1
International Mouse Knockout Project StatusTpm2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006959 VEGA Gene Model | MGI Sequence Detail 9055 C57BL/6J ±  kb
transcript OTTMUST00000016118 VEGA | MGI Sequence Detail 2175 Not Applicable 
polypeptide OTTMUSP00000007393 VEGA | MGI Sequence Detail 284 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(8) UniProt(13)
Polymorphisms
SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000533 Tropomyosin
Protein Ontology PR:000016580 tropomyosin beta chain
References
(Earliest) J:9738 Takenaga K, et al., Isolation and characterization of a cDNA that encodes mouse fibroblast tropomyosin isoform 2. Mol Cell Biol. 1988 Dec;8(12):5561-5
(Latest) J:171050 Thiagarajan RD, et al., Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
All references(56)
Other
accession IDs
MGD-MRK-15203, MGD-MRK-15206, MGD-MRK-15241

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory