Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPE
  • Mouse genes Cpe
  • Rat genes Cpe
  • Zfish genes cpe
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cpe

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004180	carboxypeptidase activity	Cpe	IMP	MGI:MGI:1856395	Mouse	PMID:7663508
Molecular Function	GO:0004180	carboxypeptidase activity	Cpe	IDA		Rat	PMID:2822027|RGD:1626225
Molecular Function	GO:0050839	cell adhesion molecule binding	CPE	IPI	UniProtKB:Q9UHC6	Human	PMID:19166515
Molecular Function	GO:0050897	cobalt ion binding	Cpe	IMP		Rat	PMID:2822027|RGD:1626225
Molecular Function	GO:0004181	metallocarboxypeptidase activity	Cpe	IMP	MGI:MGI:1856395	Mouse	PMID:9348219
Molecular Function	GO:0140677	molecular function activator activity	Cpe	IMP	MGI:MGI:1856395	Mouse	PMID:9348219
Molecular Function	GO:0042043	neurexin family protein binding	CPE	IPI	UniProtKB:Q9UHC6	Human	PMID:19166515
Molecular Function	GO:0005515	protein binding	CPE	IPI	UniProtKB:P49768-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cpe	IPI	PR:P01193	Mouse	PMID:16219686
Molecular Function	GO:0005515	protein binding	Cpe	IPI	PR:P47867	Mouse	PMID:16219686
Molecular Function	GO:0005515	protein binding	Cpe	IPI	RGD:1349318	Rat	PMID:15233624|RGD:6483328
Molecular Function	GO:0005515	protein binding	Cpe	IPI	RGD:732004	Rat	PMID:16219686|RGD:1626212
Molecular Function	GO:0005515	protein binding	Cpe	IPI	RGD:1307076	Rat	PMID:19166515|RGD:6483326
Molecular Function	GO:0005515	protein binding	Cpe	IPI	RGD:3715	Rat	PMID:19419578|RGD:6483104
Molecular Function	GO:0005515	protein binding	Cpe	IPI	RGD:620106	Rat	PMID:19553464|RGD:6483099
Molecular Function	GO:0005515	protein binding	Cpe	IPI	UniProtKB:P02866	Rat	PMID:2822027|RGD:1626225
Molecular Function	GO:0019904	protein domain specific binding	Cpe	IDA		Rat	PMID:19553464|RGD:6483099
Cellular Component	GO:0030425	dendrite	Cpe	IDA		Rat	PMID:17543468|RGD:2308893
Cellular Component	GO:0030425	dendrite	Cpe	IDA		Rat	PMID:19166515|RGD:6483326
Cellular Component	GO:0031045	dense core granule	Cpe	IDA		Rat	PMID:19553464|RGD:6483099
Cellular Component	GO:0070062	extracellular exosome	CPE	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	Cpe	IDA		Rat	PMID:10386951|RGD:6483348
Cellular Component	GO:0005615	extracellular space	Cpe	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Cpe	IDA		Rat	PMID:10206965|RGD:1626217
Cellular Component	GO:0005794	Golgi apparatus	CPE	IDA		Human	PMID:19166515
Cellular Component	GO:0005794	Golgi apparatus	Cpe	IDA		Rat	PMID:19166515|RGD:6483326
Cellular Component	GO:0005794	Golgi apparatus	Cpe	IDA		Rat	PMID:9173892|RGD:1626218
Cellular Component	GO:0045121	membrane raft	Cpe	IDA		Rat	PMID:14597614|RGD:6483330
Cellular Component	GO:0043025	neuronal cell body	Cpe	IDA		Rat	PMID:17543468|RGD:2308893
Cellular Component	GO:0043204	perikaryon	Cpe	IDA		Rat	PMID:17543468|RGD:2308893
Cellular Component	GO:0043204	perikaryon	Cpe	IDA		Rat	PMID:19166515|RGD:6483326
Cellular Component	GO:0030141	secretory granule	Cpe	IDA		Mouse	PMID:9348219
Cellular Component	GO:0030141	secretory granule	Cpe	IDA		Rat	PMID:2822027|RGD:1626225
Cellular Component	GO:0030667	secretory granule membrane	Cpe	IDA		Mouse	PMID:16219686
Cellular Component	GO:0030667	secretory granule membrane	Cpe	IDA		Rat	PMID:14597614|RGD:6483330
Cellular Component	GO:0097060	synaptic membrane	Cpe	IDA		Rat	PMID:19553464|RGD:6483099
Biological Process	GO:0003214	cardiac left ventricle morphogenesis	CPE	IMP		Human	PMID:19593212
Biological Process	GO:0034230	enkephalin processing	Cpe	IDA		Rat	PMID:6326144|RGD:6483103
Biological Process	GO:0030070	insulin processing	Cpe	IMP	MGI:MGI:1856395	Mouse	PMID:9348219
Biological Process	GO:0030070	insulin processing	Cpe	IMP	MGI:MGI:1856395	Mouse	PMID:7663508
Biological Process	GO:0030070	insulin processing	Cpe	IDA		Rat	PMID:2822027|RGD:1626225
Biological Process	GO:2000173	negative regulation of branching morphogenesis of a nerve	Cpe	IMP		Rat	PMID:19553464|RGD:6483099
Biological Process	GO:0043171	peptide catabolic process	Cpe	IDA		Rat	PMID:2822027|RGD:1626225
Biological Process	GO:0030072	peptide hormone secretion	Cpe	IMP	MGI:MGI:1856395	Mouse	PMID:16219686
Biological Process	GO:0006518	peptide metabolic process	Cpe	IDA		Rat	PMID:16219686|RGD:1626212
Biological Process	GO:0072657	protein localization to membrane	CPE	IDA		Human	PMID:19166515
Biological Process	GO:0033366	protein localization to secretory granule	Cpe	IMP	MGI:MGI:1856395	Mouse	PMID:16219686
Biological Process	GO:0016485	protein processing	Cpe	IDA		Rat	PMID:2822027|RGD:1626225
Biological Process	GO:0016055	Wnt signaling pathway	CPE	IDA		Human	PMID:22824791

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern