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Recombinase (cre) Activity

MGI collects and annotates expression and activity data for recombinase-containing transgenes and knock-in alleles.

Access Data

Find recombinase-carrying alleles

AND

Retrieve all alleles

Retrieve a list of all recombinase-containing transgenes and knock-in alleles.


Related searches

Search for recombinase-containing transgene or knock-in alleles, or floxed or frt alleles using MGI's Allele Query Form


Search for endogenous gene expression using MGI's Gene Expression Data Query Form

FAQs

How do I...

  • find existing recombinase-expressing transgenes and knock-ins that have a given promoter (driver)? FAQ
  • find the promoter (driver) that I'm looking for if it is not on the selection list? FAQ
  • find a recombinase-containing transgene or knock-in that is expressed in a specific tissue? FAQ
  • get a full list of all transgenes and knock-ins that express recombinase? FAQ
  • order mice with a desired recombinase construct? FAQ
More FAQs
Cre Portal Tutorial

Recombinase Allele Data Include

12 Jul 2016
955Recombinase-containing knock-in alleles
1610Recombinase-containing transgenes
2565Total recombinase transgenes and alleles
666Drivers in recombinase transgenes
622Drivers in recombinase knock-in alleles
3586Tissues in recombinase specificity assays
More...

Recombinase Project News

29 Oct 2009
  • Data about cre-containing transgenes and knock-ins and their tissue specific activity are being curated from the scientific literature and integrated from projects underway at collaborating organizations. (See the Collaborators tab, below).
  • We are part of the CREATE (Coordination of resources for conditional expression of mutated mouse alleles) consortium.
  • List of available strains expressing cre
Cre is currently the most commonly used recombinase. It catalyzes site-specific recombination of DNA between loxP sites, thus making possible conditional mutagenesis, where specific genes can be knocked out in particular tissues and at particular developmental time points. Other non-cre recombinases (such as Flp, Dre, phiC31, etc.) and various inducible forms of recombinases have been and are being developed. We are curating data about all recombinase-containing transgenes and knock-ins developed in mice to provide a comprehensive resource delineating known activity patterns and allowing users to find relevant mouse resources for their studies.
Available data will continue to increase. To retrieve all recombinase-containing transgenes and knock-in alleles, use RETRIEVE ALL ALLELES, above.
The Recombinase Activity project is funded by NIH grants OD011190 and HD062499.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory