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All mouse models of blood platelet disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Glanzmann's thrombasthenia |
Itgb3tm1Hyn/Itgb3tm1.1Wlbcr Tg(Pf4-icre)Q3Rsko/0 |
involves: 129S2/SvPas * C57BL/6 | J:224675 | View | |||
| gray platelet syndrome | Nbeal2gps/Nbeal2gps | 129S1/SvImJ-Nbeal2gps | J:236370 | View | ||||
| gray platelet syndrome | Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi | C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi | J:220801 | View | ||||
| gray platelet syndrome | Nbeal2tm1Lex/Nbeal2tm1Lex | involves: 129S5/SvEvBrd * C57BL/6J | J:201413 | View | ||||
| MYH-9 related disease | Myh9tm1.1(MYH9*)Mjk/Myh9+ | B6.Cg-Myh9tm1.1(MYH9*)Mjk | J:175367 | View | ||||
| MYH-9 related disease | Myh9tm1.1(MYH9*)Mjk/Myh9tm1.1(MYH9*)Mjk | B6.129-Myh9tm1.1(MYH9*)Mjk | J:175367 | View | ||||
| MYH-9 related disease | Myh9tm7.1Rsad/Myh9+ | involves: BALB/cJ | J:175367 | View | ||||
| MYH-9 related disease | Myh9tm7.1Rsad/Myh9tm7.1Rsad | involves: BALB/cJ | J:175367 | View | ||||
| platelet-type bleeding disorder 8 | P2ry12tm1Cjf/P2ry12tm1Cjf | involves: 129 | J:70017 | View | ||||
| platelet-type bleeding disorder 8 | P2ry12tm1Pcon/P2ry12tm1Pcon | involves: 129P2/OlaHsd * C57BL/6 | J:84917 | View | ||||
| platelet-type bleeding disorder 10 | Cd36tm1Mfe/Cd36tm1Mfe | involves: 129S1/Sv * C57BL/6 | J:56081 | View | ||||
| platelet-type bleeding disorder 16 | Itga2btm1Tlr/Itga2btm1Tlr | either: (involves: 129S1/Sv * 129X1/SvJ * BALB/c) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) | J:63961 | View | ||||
| platelet-type bleeding disorder 16 | Itgb3tm1Hyn/Itgb3tm1Hyn | involves: 129S2/SvPas * C57BL/6 | J:52262 | View | ||||
| thrombocytopenia |
Gata1tm1Mym/Y Tg(Gata1*V205G)1Mym/0 |
involves: C57BL/6 * DBA/2 | J:89054 | View | ||||
| | congenital amegakaryocytic thrombocytopenia | Mpltm1Fjs/Mpltm1Fjs | involves: 129 * C57BL/6J | J:87416 | View | |||
| platelet storage pool deficiency | Ap3b1pe-rim2/Ap3b1pe-rim2 | involves: B10.A(R201) * C57BL/10Slc | J:42685 | View | ||||
| platelet storage pool deficiency | Ap3b1pe/Ap3b1pe | B6.C3-Ap3b1pe/J | J:7327 | View | ||||
| platelet storage pool deficiency | Ap3b1pe/Ap3b1pe | involves: C3H/He | J:7327 | View | ||||
| platelet storage pool deficiency | Ap3d1mh/Ap3d1mh | B6.C3-Grxcr1pi | J:29151 | View | ||||
| platelet storage pool deficiency | Bloc1s5mu/Bloc1s5mu | CHMU/Le | J:29151 | View | ||||
| platelet storage pool deficiency | Bloc1s5mu/Bloc1s5mu | involves: STOCK t | J:29151 | View | ||||
| platelet storage pool deficiency | Bloc1s6pa/Bloc1s6pa | B6.Cg-Bloc1s6pa/J | J:7327 | View | ||||
| platelet storage pool deficiency | Dock7m/Dock7m | B6.D(Cg)-Dock7m | J:45425 | View | ||||
| platelet storage pool deficiency | Dtnbp1sdy/Dtnbp1sdy | involves: DBA/2J | J:1958 | View | ||||
| platelet storage pool deficiency | Hps1ep/Hps1ep | B6.C3Fe-Hps1ep/J | J:7327 | View | ||||
| platelet storage pool deficiency | Hps1ep/Hps1ep | involves: C3HeB/FeJ * C57BL/6J | J:7327 | View | ||||
| platelet storage pool deficiency | Hps3coa-6J/Hps3coa-6J | C3H/HeJ-Hps3coa-6J/J | J:63693 | View | ||||
| platelet storage pool deficiency | Hps3coa/Hps3coa | involves: C57BL/10J | J:9300 | View | ||||
| platelet storage pool deficiency | Hps4le/Hps4le | B6.C3-Pde6brd1 Hps4le | J:7327 | View | ||||
| platelet storage pool deficiency | Hps5ru2-mr/Hps5ru2-mr | B6.Cg-Hps5ru2-mr/Re | J:7327 | View | ||||
| platelet storage pool deficiency | Hps5ru2-mr/Hps5ru2-mr | Not Specified | J:7327 | View | ||||
| platelet storage pool deficiency | Lystbg-J/Lystbg-J | C57BL/6J-Lystbg-J/J | J:7327 | View | ||||
| platelet storage pool deficiency | Rab27aash/Rab27aash | involves: C3H/HeDiSn | J:63231 | View | ||||
| platelet storage pool deficiency |
Rab27aash/Rab27aash Rab27btm1.2Seab/Rab27btm1.2Seab |
involves: 129X1/SvJ * C3H/HeSn * C57BL/6J | J:120307 | View | ||||
| platelet storage pool deficiency | Rab27btm1.2Seab/Rab27btm1.2Seab | involves: 129X1/SvJ * C57BL/6J | J:120307 | View | ||||
| platelet storage pool deficiency | Slc7a11sut/Slc7a11sut | C3H/HeSnJ-Slc7a11sut/J | J:31616 | View | ||||
| Additional Complex Models | acquired thrombocytopenia |
Tg(FCGR2A)11Mkz/0 Tg(PF4)#Zcy/0 |
involves: C57BL/6 * SJL | J:72220 | View | |||
| platelet storage pool deficiency |
a/a Hps6ru/Hps6ru |
B6.Cg-Hps6ru | J:7327 | View | ||||