Excel File Text File All mouse models of sphingolipidosis with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      combined saposin deficiency Psaptm1Suz/Psaptm1Suz involves: 129P2/OlaHsd J:33477 View
Fabry disease Glatm1Kul/Y involves: 129S4/SvJae * C57BL/6 J:39394, J:187258 View
Fabry disease Glatm1Kul/Glatm1Kul
Tg(CAG-A4GALT)#Sais/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6JJms J:206001 View
Fabry disease Glatm1Kul/Y
Tg(CAG-A4GALT)#Sais/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6JJms J:206001 View
Gaucher's disease type I Gbatm1.1Karl/Gbatm1.1Karl involves: 129S1/Sv * 129X1/SvJ J:113751 View
Gaucher's disease type I Gbatm1Clk/Gbatm1.1Clk
Tg(Tek-cre)12Flv/0
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J J:117763 View
Gaucher's disease type I Gbatm1Karl/Gbatm1.1Karl
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:113751 View
Gaucher's disease type I Gbatm1.1Pmis/Gbatm1.1Pmis
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA J:167081 View
Gaucher's disease type I Gbatm1.1Pmis/Gbatm1.2Pmis
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA J:167081 View
Gaucher's disease type II Gbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N J:127108 View
Gaucher's disease type II Gbatm1Nsb/Gbatm1Nsb involves: 129S/SvEv * C57BL/6 J:1100 View
GM2 gangliosidosis, AB variant Gm2atm1Rlp/Gm2atm1Rlp involves: 129S4/SvJae * C57BL/6 J:41950 View
Krabbe disease Galctwi/Galctwi B6.CE-Galctwi/J J:6390, J:6423, J:165361, J:170081 View
Krabbe disease Galcm4Btlr/Galcm4Btlr C57BL/6J-Galcm4Btlr J:307652 View
Krabbe disease Galctm1Wngr/Galctm1Wngr involves: 129S2/SvPas J:78691 View
metachromatic leukodystrophy Arsatm1Gie/Arsatm1Gie involves: 129P2/OlaHsd * C57BL/6J J:37978, J:52310 View
metachromatic leukodystrophy Psaptm2Ggb/Psaptm2Ggb involves: 129S/SvEv * C57BL/6J J:137650 View
mucosulfatidosis Sumf1Gt(RST760)Byg/Sumf1Gt(RST760)Byg involves: 129P2/OlaHsd * C57BL/6 J:120146 View
Niemann-Pick disease type C1 Npc1tm1Tacf/Npc1tm1Tacf B6(Cg)-Npc1tm1Tacf J:266795 View
Niemann-Pick disease type C1 Npc1tm1Tacf/Npc1tm2Tacf B6(Cg)-Npc1tm1Tacf Npc1tm2Tacf J:266795 View
Sandhoff disease Hexblysd/Hexblysd B6.Cg-Hexblysd/J J:301674 View
Sandhoff disease Hexbtm1Grv/Hexbtm1Grv either: (involves: 129P2/Ola * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * C57L/6J) J:30899 View
Sandhoff disease Fcer1gtm1Rav/Fcer1gtm1Rav
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 J:87617 View
Sandhoff disease Ccl3tm1Unc/Ccl3tm1Unc
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 J:90687 View
Sandhoff disease Ccl3tm1Unc/Ccl3+
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 J:90687 View
Sandhoff disease Hexbtm1Rlp/Hexbtm1Rlp involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 J:87617 View
Sandhoff disease Hexbtm1Rlp/Hexbtm1Rlp involves: 129S4/SvJae * C57BL/6 J:29268, J:190450 View
Sandhoff disease Hexbtm1Rlp/Hexbtm1Rlp
Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0
involves: 129S4/SvJae * C57BL/6 * CBA J:190450 View
Sandhoff disease Hexbtm1Rlp/Hexbtm1Rlp
Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0
involves: 129S4/SvJae * C57BL/6 * CBA J:190450 View
Tay-Sachs disease Hexatm1Grv/Hexatm1Grv involves: 129P2/Ola * C57BL/6J J:30899 View
Tay-Sachs disease Hexatm1Cota/Hexatm1Cota involves: 129S2/SvPas * C57BL/6 J:30435 View
Tay-Sachs disease Hexatm1Rlp/Hexatm1Rlp involves: 129S4/SvJae * C57BL/6 J:21008 View
      Gaucher's disease Gbatm2Ggb/Gbatm2Ggb
Psaptm1Suz/Psaptm1Suz
involves: 129P2/OlaHsd * 129S5/SvEvBrd J:174780 View
Gaucher's disease Gbatm1Rlp/Gbatm1Rlp involves: 129S4/SvJae * C57BL/6 J:76409 View
Gaucher's disease Gbatm3Ggb/Gbatm3Ggb involves: 129S5/SvEvBrd J:86334 View
Gaucher's disease Gbatm1Ggb/Gbatm1Ggb involves: 129S5/SvEvBrd * C57BL/6 J:86334 View
Gaucher's disease Gbatm2Ggb/Gbatm2Ggb involves: 129S5/SvEvBrd * C57BL/6 J:86334 View
Gaucher's disease Gbatm4Ggb/Gbatm4Ggb involves: 129S5/SvEvBrd * C57BL/6 J:86334 View
Gaucher's disease Gbatm2Ggb/Gbatm1Nsb involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6 J:86334 View
Gaucher's disease Gbatm3Ggb/Gbatm1Nsb involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6 J:86334 View
Gaucher's disease Gbatm4Ggb/Gbatm1Nsb involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6 J:86334 View
GM1 gangliosidosis Glb1tm1Adz/Glb1tm1Adz involves: 129/Sv * C57BL/6 J:98543 View
GM1 gangliosidosis Glb1tm1Adz/Glb1tm1Adz involves: 129P2/OlaHsd J:38620 View
GM1 gangliosidosis Glb1tm1Jmat/Glb1tm1Jmat involves: C57BL/6 * CBA * ICR J:40522, J:43534 View
Krabbe disease Psaptm2Suz/Psaptm2Suz involves: 129S/SvEv * C57BL/6J J:78223 View
Niemann-Pick disease Npc1tm1.1Dso/Npc1tm1.1Dso B6.129-Npc1tm1.1Dso J:221855 View
Niemann-Pick disease Npc1m1N/Npc1m1N B6.C-Npc1m1N J:157113 View
Niemann-Pick disease Npc1m1N/Npc1tm1.2Apl B6.Cg-Npc1m1N/Npc1tm1.2Apl J:157113 View
Niemann-Pick disease Npc1m1N/Npc1tm1.1Apl
Tg(CAG-cre/Esr1*)5Amc/0
B6J.Cg-Npc1m1N/Npc1tm1.1Apl Tg(CAG-cre/Esr1*)5Amc J:176888 View
Niemann-Pick disease Npc1m1N/Npc1m1N BALB/c-Npc1m1N J:172769 View
Niemann-Pick disease Npc1m1N/Npc1m1N BALB/cNctr-Npc1m1N/J J:182268, J:209834 View
Niemann-Pick disease Npc1nmf164/Npc1nmf164 C57BL/6J-Npc1nmf164/J J:179744 View
Niemann-Pick disease Npc1spm/Npc1spm C57BLKS/J-Npc1spm/J J:6833 View
Niemann-Pick disease Apptm1Dbo/Apptm1Dbo
Npc1m1N/Npc1m1N
C.Cg-Apptm1Dbo Npc1m1N J:172769 View
Niemann-Pick disease Abcb1atm1Bor/Abcb1atm1Bor
Npc1m1N/Npc1m1N
involves: 129/Ola * BALB/c J:76395 View
Niemann-Pick disease Smpd1tm1Wst/Smpd1tm1Wst involves: 129P2/OlaHsd * C57BL/6 J:26748 View
Niemann-Pick disease Npc2tm1Plob/Npc2tm1Plob involves: 129S1/Sv * BALB/c J:204311 View
Niemann-Pick disease Npc1m1N/Npc1m1N involves: 129S1/Sv * BALB/c * C57BL/6 J:89617 View
Niemann-Pick disease Npc1m1N/Npc1m1N
Npc2tm1Plob/Npc2tm1Plob
involves: 129S1/Sv * BALB/c * C57BL/6 J:89617 View
Niemann-Pick disease Npc2tm1Plob/Npc2tm1Plob involves: 129S1/Sv * BALB/c * C57BL/6 J:89617 View
Niemann-Pick disease Smpd1tm1Esc/Smpd1tm1Esc involves: 129S1/Sv * C57BL/6J J:26732, J:35076, J:44401, J:70489, J:78875, J:81982 View
Niemann-Pick disease Npc1m1N/Npc1m1N
Nr1h2tm1Djm/Nr1h2tm1Djm
involves: 129S6/SvEvTac * BALB/c J:130969 View
Niemann-Pick disease Npc1tm1Mbjg/Npc1tm1Mbjg involves: 129S6/SvEvTac * C57BL/6J J:176587 View
Niemann-Pick disease Npc1m1N/Npc1m1N involves: BALB/c J:18511, J:76733, J:81305, J:130969, J:204311 View
Niemann-Pick disease Npc1m1N/Npc1m1N involves: BALB/c * C3H/HeJ * C57BL/6J J:188345 View
Niemann-Pick disease Npc1m1N/Npc1m1N
Tg(PRNP-APPSweInd)8Dwst/0
involves: BALB/c * C3H/HeJ * C57BL/6J J:188345 View
Niemann-Pick disease fm/fm involves: CBA/H J:5696 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      Gaucher's disease Psaptm1Suz/Psaptm2.1Juma involves: 129 * 129P2/OlaHsd * C57BL/6J * FVB/N J:283977 View
Gaucher's disease Psaptm2.1Juma/Psaptm2.1Juma involves: 129 * C57BL/6J * FVB/N J:283977 View