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Human Disease and Mouse Model Detail
Human Disease Amyotrophic Lateral Sclerosis 10 with or without Frontotemporal Dementia;
OMIM ID: 612069
Human Phenotype Ontology associations
Synonyms Amyotrophic Lateral Sclerosis
View all models View ALL (16) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     TARDBP* Tardbp* View 15 models HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu View 1 model
  Tg(Prnp-TARDBP)3cPtrc View 1 model
  Tg(Prnp-TARDBP)4Jlel View 1 model
  Tg(Prnp-TARDBP*A315T)23Jlel View 1 model
  Tg(Prnp-TARDBP*A315T)95Balo View 1 model
  Tg(TARDBP)#Jpj View 1 model
  Tg(TARDBP*A315T)#Jpj View 1 model
  Tg(TARDBP*G348C)#Jpj View 1 model
  Tg(tetO-TARDBP)12Vle View 1 model
  Tg(tetO-TARDBP*)4Vle View 2 models
  Tg(Thy1-TARDBP)4Singh View 2 models
  Tg(Thy1-TARDBP)6Singh View 1 model
  Tg(Thy1-TARDBP*)BOddo View 1 model
References Disease References using Mouse Models (15)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory