Phenotypes Associated with This Genotype

Genotype
MGI:5902151

• Allelic Composition: Rhox13^tm1.2Chge/Y
• Genetic Background: B6NCrl.129P2(Cg)-Rhox13^tm1.2Chge

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

decreased male germ cell number ( J:237048 )

♂ • 3.8-fold reduction in the number of round spermatids per area of seminiferous tubules and an apparent difference in the number of tubules containing round spermatids at P20

♂ • normal numbers of round spermatids at P22

oligozoospermia ( J:237048 )

♂ • 40% reduced number of cauda epididymal sperm in virgin males at P56

♂ • normal numbers of cauda epididymal sperm in breeding males at P120

increased male germ cell apoptosis ( J:237048 )

♂ • approximately three-fold increase in cleaved-Parp1-positive (apoptotic) germ cells at P12 and P20

reproductive system

decreased male germ cell number ( J:237048 )

♂ • 3.8-fold reduction in the number of round spermatids per area of seminiferous tubules and an apparent difference in the number of tubules containing round spermatids at P20

♂ • normal numbers of round spermatids at P22

oligozoospermia ( J:237048 )

♂ • 40% reduced number of cauda epididymal sperm in virgin males at P56

♂ • normal numbers of cauda epididymal sperm in breeding males at P120

increased male germ cell apoptosis ( J:237048 )

♂ • approximately three-fold increase in cleaved-Parp1-positive (apoptotic) germ cells at P12 and P20