Analysis Tools
reproductive system
 |
• elongated
|
|
|
• defects in the maintenance of undifferentiated spermatogonia
|
|
|
• reduced primordial germ cells in male mice
• however, no primordial germ cells are detected outside of the gonadal ridge
|
|
|
• increased apoptosis in testes, at the periphery of seminiferous tubules and in differentiated spermatids
|
|
|
• enriched Sertoli cells
|
|
|
• at 4 and 10 weeks
|
|
|
• atrophic
|
small testis
(
J:224588
)
|
|
• at 4 and 10 weeks
|
growth/size/body
homeostasis/metabolism
|
|
• increase in the number of persistent double strand breaks in male germ cells
• however, male germ cells exhibit normal meiotic recombination
|
cellular
|
|
• elongated
|
|
|
• defects in the maintenance of undifferentiated spermatogonia
|
|
|
• reduced primordial germ cells in male mice
• however, no primordial germ cells are detected outside of the gonadal ridge
|
|
|
• increased apoptosis in testes, at the periphery of seminiferous tubules and in differentiated spermatids
|
|
|
• increase in the number of persistent double strand breaks in male germ cells
• however, male germ cells exhibit normal meiotic recombination
|
endocrine/exocrine glands
|
|
• enriched Sertoli cells
|
|
|
• at 4 and 10 weeks
|
|
|
• atrophic
|
small testis
(
J:224588
)
|
|
• at 4 and 10 weeks
|
